RT Journal Article SR Electronic T1 Pneumology in COVID-19 times: facing misleading diagnosis JF European Respiratory Journal JO Eur Respir J FD European Respiratory Society SP PA839 DO 10.1183/13993003.congress-2021.PA839 VO 58 IS suppl 65 A1 Javier Poyo Molina A1 Koral Fernández De Roitegui Pérez A1 Clara Ortega Michel A1 Irantzu Elorza Sagasta A1 Miguel Ángel Sánchez De Toro A1 Paula Bordallo Vázquez A1 Blanca Virgala Ocio A1 Leire Álvarez Peña A1 David Bravo Blanco A1 Francisco Javier Ribas Solís A1 Laura Tomás López YR 2021 UL http://erj.ersjournals.com/content/58/suppl_65/PA839.abstract AB Introduction: COVID-19 diagnosis is established on the basis of clinical findings, compatible radiography and the determination by PCR of the presence of SARS-CoV-2 virus genetic material or its antigens in the respiratory tract, being the bronchoalveolar lavage (BAL) the sample which offers best results. The aim of this work is to study BAL diagnostic utility in patients with suspected COVID-19, who have had a negative SARS-Cov-2 PCR result with nasopharyngeal swab.Methods: An observational, descriptive and retrospective study was conducted in patients with clinical and radiographic findings compatible with COVID-19 who have had a negative SARS-CoV-2 result with nasopharyngeal swab. A bronchoscopy was performed to analyse PCR of SARS-CoV-2 with BAL.Results: From 06/03/2020 to 19/01/2021, 36 bronchoscopies were performed on 36 different patients (23 males [63.89%], average age of 40 years [22-89]). 27 were held in endoscopy room and 9 in ICU. PCR for SARS-CoV-2 with BAL was positive in 8 patients, establishing the diagnosis of COVID-19. The diagnosis of the remaining 28 patients is reflected in Figure 1. There were no serious complications associated with the procedure. 6 patients died during the admission.Conclusions: The performance of a BAL in patients with suspected COVID-19 and a negative SARS-CoV-2 PCR result with nasopharyngeal swab is a safe procedure, being a useful tool to confirm the disease and to advance the diagnosis in the rest of cases.FootnotesCite this article as: European Respiratory Journal 2021; 58: Suppl. 65, PA839.This abstract was presented at the 2021 ERS International Congress, in session “Prediction of exacerbations in patients with COPD”.This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only).