RT Journal Article SR Electronic T1 The impact of pulmonary tuberculosis on the quality of life of Colombian patients and their families. A case-control study JF European Respiratory Journal JO Eur Respir J FD European Respiratory Society SP PA3637 DO 10.1183/13993003.congress-2021.PA3637 VO 58 IS suppl 65 A1 Benavides Córdoba, Vicente Andrés A1 Garces, David A1 Cañon, Mariana A1 Benavides, Yurany A1 Beltran, Marcela A1 Betancourt-Peña, Jhonatan YR 2021 UL http://erj.ersjournals.com/content/58/suppl_65/PA3637.abstract AB Introduction: Pulmonary tuberculosis (TB), creates a social problem since there are predisposing factors that, in addition, affects the person at multidimensional dimensions.Aim: To determine the association between the health-related quality of life (HRQoL) in patients with pulmonary TB and their family contacts in Cali - Colombia.Materials and methods: A case-control study. The WHOQoL-BREF questionnaire was used to measure HRQoL. The association was analyzed by Fisher test or Chi-square; Odds Ratio and confidence interval were calculated.Results: Seventy participants entered the study, 35 with TB (cases), and 35 family contacts (controls). Regarding the characteristics of the population, differences were found in cigarette and recreational drugs use in cases. In the evaluation of the quality of life; In the physical, psychological and social domains, the cases presented lower levels compared to the controls (p <0.05) (Table 1)Conclusions: The HRQoL of people with TB was lower compared to their family controls, not only in aspects related to the physical component. It is necessary to promote comprehensive interventions in this population. WHOQoL DomainsCases n: 35Controls n: 35OR (CI 95%)p-ValuePhysicalGood2432Deficient1134.88 (1.27 - 19.48)< 0.05PsychologicalGood2634Deficient9111.77 (1.4 - 98.9)< 0.01SocialGood1629Deficient1965.47 (1.96 - 17.29)< 0.01EnvironmentGood2025Deficient15101.87 (0.69 - 5.06)nsFootnotesCite this article as: European Respiratory Journal 2021; 58: Suppl. 65, PA3637.This abstract was presented at the 2021 ERS International Congress, in session “Prediction of exacerbations in patients with COPD”.This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only).