TY - JOUR T1 - Adult women with asthma and diabetes have increased body weight and fat percentage compared to women with only diabetes JF - European Respiratory Journal JO - Eur Respir J DO - 10.1183/13993003.congress-2021.PA3119 VL - 58 IS - suppl 65 SP - PA3119 AU - Apostolos Bossios AU - Daniel P. Andersson AU - Daniel Eriksson-Hogling AU - Mikael Rydén Y1 - 2021/09/05 UR - http://erj.ersjournals.com/content/58/suppl_65/PA3119.abstract N2 - Background: Obesity-related asthma phenotype is more often reported in women, and type 2 diabetes is a common co-morbidity. However, to what degree obesity status, defined by body weight and body fat mass, associates with asthma and/or diabetes and how this is impacted by gender it is still unclear.Aim: To evaluate the obesity status, expressed as BMI and fat percentage in women and men with asthma and diabetes compared to ones with only diabetes.Methods: Retrospective data; diabetes diagnosis, self-reported asthma, BMI (kg/m2) and body fat percentage, were collected from consecutively recruited patients and research subjects to different clinical academic studies at the Endocrinology and Diabetes Unit at the Karolinska University Hospital.Results: Data from 6403 adults were evaluated (mean age 43,52 ± 11,53 SD, 74,8 % females, median BMI 36,5;26,1-41,4, Q1-Q3 and median body fat percentage 45,53%: 31,61-54,13, Q1-Q3). In 854 individuals with diabetes, 6,55% reported asthma (mean age 50,77 ± 10,73 SD), and 93,45 % did not (mean age 52,29 ± 20,51 SD). Patients with diabetes and asthma had significantly higher BMI (p= 0,003) and body fat percentage (p= 0,002) compared to those with only diabetes. When divided according to sex, no differences were found in men, while in women, patients with asthma and diabetes had higher BMI (p= 0,000) and body fat percentage (p= 0,000) compared to ones with only diabetes.Conclusions: Patients with diabetes and asthma display higher BMI and body fat percentages compared to patients with only diabetes. This difference is only observed among women, suggesting them as a target group for intensified weight loss treatments.FootnotesCite this article as: European Respiratory Journal 2021; 58: Suppl. 65, PA3119.This abstract was presented at the 2021 ERS International Congress, in session “Prediction of exacerbations in patients with COPD”.This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only). ER -