RT Journal Article SR Electronic T1 Adult women with asthma and diabetes have increased body weight and fat percentage compared to women with only diabetes JF European Respiratory Journal JO Eur Respir J FD European Respiratory Society SP PA3119 DO 10.1183/13993003.congress-2021.PA3119 VO 58 IS suppl 65 A1 Apostolos Bossios A1 Daniel P. Andersson A1 Daniel Eriksson-Hogling A1 Mikael Rydén YR 2021 UL http://erj.ersjournals.com/content/58/suppl_65/PA3119.abstract AB Background: Obesity-related asthma phenotype is more often reported in women, and type 2 diabetes is a common co-morbidity. However, to what degree obesity status, defined by body weight and body fat mass, associates with asthma and/or diabetes and how this is impacted by gender it is still unclear.Aim: To evaluate the obesity status, expressed as BMI and fat percentage in women and men with asthma and diabetes compared to ones with only diabetes.Methods: Retrospective data; diabetes diagnosis, self-reported asthma, BMI (kg/m2) and body fat percentage, were collected from consecutively recruited patients and research subjects to different clinical academic studies at the Endocrinology and Diabetes Unit at the Karolinska University Hospital.Results: Data from 6403 adults were evaluated (mean age 43,52 ± 11,53 SD, 74,8 % females, median BMI 36,5;26,1-41,4, Q1-Q3 and median body fat percentage 45,53%: 31,61-54,13, Q1-Q3). In 854 individuals with diabetes, 6,55% reported asthma (mean age 50,77 ± 10,73 SD), and 93,45 % did not (mean age 52,29 ± 20,51 SD). Patients with diabetes and asthma had significantly higher BMI (p= 0,003) and body fat percentage (p= 0,002) compared to those with only diabetes. When divided according to sex, no differences were found in men, while in women, patients with asthma and diabetes had higher BMI (p= 0,000) and body fat percentage (p= 0,000) compared to ones with only diabetes.Conclusions: Patients with diabetes and asthma display higher BMI and body fat percentages compared to patients with only diabetes. This difference is only observed among women, suggesting them as a target group for intensified weight loss treatments.FootnotesCite this article as: European Respiratory Journal 2021; 58: Suppl. 65, PA3119.This abstract was presented at the 2021 ERS International Congress, in session “Prediction of exacerbations in patients with COPD”.This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only).