RT Journal Article SR Electronic T1 Study for evaluation of using transthoracic lung ultrasound in diagnosis of pulmonary embolism JF European Respiratory Journal JO Eur Respir J FD European Respiratory Society SP PA3546 DO 10.1183/13993003.congress-2021.PA3546 VO 58 IS suppl 65 A1 Muhammed Abdelkader, Asmaa Abdelkader A1 Zidan, Mohamed A1 Eshmawey, Heba A1 Gharraf, Heba YR 2021 UL http://erj.ersjournals.com/content/58/suppl_65/PA3546.abstract AB Background: As pulmonary embolism (PE) could be fatal, its early diagnosis is crucial. Its diagnosis depending on pre-test probability necessitates a combination of clinical, laboratory, and imaging data.Aim: To determine the reliability of lung ultrasound (LUS) in diagnosis of PE in hemodynamically stable patients.Methodology: In this prospective clinical study, 30 hemodynamically stable patients (19 men, 11 women, age 22-70 years) with suspected PE and moderate to high clinical probability on Wells score were investigated using LUS by a pulmonologist. PE was confirmed if at least a single hypoperfused (by color doppler imaging), hypoechoic, round or wedge-shaped pleural based consolidation was detected with or without pleural effusion,(figure1). Final diagnosis was made by CT pulmonary angiography (CTPA) (reference method). Results: PE was diagnosed in 18 patients. LUS was found true positive in 11 patients, false positive in 1 patient, true negative in 11 patients, false negative in 7 patients. Sensitivity, specificity, positive predictive value, negative predictive value was 61%, 91.6%, 91.6%, 61% respectively.Conclusion: LUS is a reliable diagnostic method in clinically stable patients with moderate to high suspicion for PE when used with color doppler imaging. Although, a negative LUS study cannot rule out PE with certainty, but positive findings may decrease the current abuse of CTPA with unnecessary contrast exposure.FootnotesCite this article as: European Respiratory Journal 2021; 58: Suppl. 65, PA3546.This abstract was presented at the 2021 ERS International Congress, in session “Prediction of exacerbations in patients with COPD”.This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only).