RT Journal Article
SR Electronic
T1 Approaches to TB prediction in patients with COPD
JF European Respiratory Journal
JO Eur Respir J
FD European Respiratory Society
SP PA2438
DO 10.1183/13993003.congress-2021.PA2438
VO 58
IS suppl 65
A1 Anna Mordyk
A1 Natalia Bagisheva
A1 Marina Moiseeva
YR 2021
UL http://erj.ersjournals.com/content/58/suppl_65/PA2438.abstract
AB xThe high-risk groups should be of greatest interest for TB development in reducing the incidence of it.Purpose: to determine the contribution of social and medical factors to the TB development in patients with COPD and to determine the possibility of influencing them for the prevention of tuberculosis.Materials and methods: The study includes 204 patients diagnosed with the newly identified TB and COPD, of whom 180 men (88.2%), mean age (Me 25; 75) - 48.45 (38; 57) years. The method of the main factors with varimax rotation, the Gutmann method with the scree plot effect was used. 15 parameters determining the probability of developing TB in patients with COPD were accepted for consideration. Variance explained by 6 consecutive significant factors was 76.5% of the contribution of all factors, indicating sufficient adequacy of the developed model (p < 0.05).Results and Discussion: The 1 factor is tobacco dependence, its contribution is 27.6%. The 2 factor included marital status and the presence of children, its contribution is 12.6%. The 3 factor took into account drug dependence and the presence of HIV infection, with a contribution of 12.4%. The 4 factor is male gender, with a contribution of 8.1%. The 5 factor is age, with a contribution of 8.0%. The 6 factor included the absence of housing, with a contribution of 7.7%. Risk factors did not include staying in institutions of the federal penal system, the presence of dependence on alcohol, and the regularity of fluorography.Conclusion: Risk groups for TB among COPD patients are older men who are socially vulnerable, without their own housing, living in poor socio-hygienic conditions, without families and children, with HIV infection, injecting drug users, smokers.FootnotesCite this article as: European Respiratory Journal 2021; 58: Suppl. 65, PA2438.This abstract was presented at the 2021 ERS International Congress, in session “Prediction of exacerbations in patients with COPD”.This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only).