TY - JOUR T1 - Influence of residential land cover on hospitalizations: a population-based study JF - European Respiratory Journal JO - Eur Respir J DO - 10.1183/13993003.congress-2021.PA1787 VL - 58 IS - suppl 65 SP - PA1787 AU - Sara Maio AU - Sandra Baldacci AU - Anna Angino AU - Sofia Tagliaferro AU - Isabella Annesi-Maesano AU - Salvatore Fasola AU - Stefania La Grutta AU - Giovanni Viegi Y1 - 2021/09/05 UR - http://erj.ersjournals.com/content/58/suppl_65/PA1787.abstract N2 - Background: recent research showed that residential land cover may affect health outcomes in children; the influence on adult health status, however, still needs to be clarified.Aim: to assess the influence of residential land cover on hospitalizations in a general population sample.Methods: 2658 subjects (females: 55.0%; age range: 15-97) living in Pisa, Italy, were investigated in 1991-93 through a questionnaire on health status and risk factors. Hospitalizations for cardiovascular (CVD), cancer (CANC) and respiratory (RESP) diseases were followed-up until 2015. Land-cover exposures within a 1000 m buffer from each subjects’ home address were computed using data from the CORINE program (CLC 1990). The associations of hospitalizations (at least one from 1996 to 2015) with land coverage were estimated using multinomial logistic regression models adjusted for the main confounding factors (reference category: subjects alive and not hospitalized between 1996-2015).Results: the following cumulative rates of CVD, CANC and RESP hospitalizations emerged: 41.6%, 25.5% and 19.8%. A 10% increase in agricultural space coverage was associated with lower risk of CVD (OR [95% CI]: 0.93 [0.89-0.98]) and RESP (OR 0.92 [0.87-0.97]) hospitalizations; vice versa, a 10% increase in grey and blue space coverage was associated with higher risk of CVD (OR 1.07 [1.02-1.12]; OR 1.69 [1.10-2.58], respectively), RESP (OR 1.08 [1.02-1.14]; OR 2.30 [1.41-3.76], respectively) and CANC (OR 1.73 [1.10-2.73], only for blue spaces) hospitalizations.Conclusions: Living close to agricultural space may provide protective effects on health outcomes, while exposure to grey and blue (i.e. Arno river) spaces may have adverse effects.FootnotesCite this article as: European Respiratory Journal 2021; 58: Suppl. 65, PA1787.This abstract was presented at the 2021 ERS International Congress, in session “Prediction of exacerbations in patients with COPD”.This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only). ER -