RT Journal Article
SR Electronic
T1 Early profiling of low-risk SARS-CoV-2 pneumonia for ward allocation
JF European Respiratory Journal
JO Eur Respir J
FD European Respiratory Society
SP PA3659
DO 10.1183/13993003.congress-2021.PA3659
VO 58
IS suppl 65
A1 Méndez, Raúl
A1 González-Jiménez, Paula
A1 Latorre, Ana
A1 Serrano, Leyre
A1 Ruiz, Luis Alberto
A1 Zalacaín, Rafael
A1 España, Pedro Pablo
A1 Uranga, Ane
A1 Cillóniz, Catia
A1 Torres, Antoni
A1 Menéndez, Rosario
YR 2021
UL http://erj.ersjournals.com/content/58/suppl_65/PA3659.abstract
AB Introduction: The new coronavirus causing COVID-19 has spread worldwide, leading to a shortage of ICU and ward beds, thereby prompting the need to triage mild vs severe pneumonia. The objective of our study is to identify patients with low-risk COVID-19 pneumonia who do not require ICU admission and/or do not die during hospitalization, based on analytical and clinical data obtained in the initial evaluation.Methods: To this end, a multicenter cohort was defined in 4 hospitals with 1274 hospitalized patients. The cohort was stratified into two groups: (1) low-risk patients (hospitalized pneumonia that does not require ICU admission or die during hospitalization) and (2) severe pneumonia (direct or subsequent ICU admission and/or death). Demographic variables, analytics, and lower ATS/IDSA criteria were collected. A univariate study was conducted and, the variables found as significant, were introduced in a multivariate analysis of logistic regression.Results: Five independent associated factors were identified as predictors of no ICU requirement and/or death: <3 IDSA/ATS minor criteria (OR 0.23, 95% CI 0.15- 0.37), SpO2/FiO2 > 450 (OR 0.23, 0.15-0.36), CRP <60 mg/L (OR 0.45, 0.29-0.72), lymphocyte > 723 cells/mL (OR 0.54, 0.36-0.81) and urea <40 mg/dL (OR 0.65, 0.43-0.99), with an AUC of 0.80 (0.77-0.84).Conclusions: In conclusion, early identification of low-risk SARS-CoV-2 pneumonia is feasible based on initial biochemical findings and using lower ATS/IDSA criteria. This is useful for the quickly decision of hospital admission when there are different hospitalization alternatives.Funding: Instituto de Salud Carlos III (COV20/00385).FootnotesCite this article as: European Respiratory Journal 2021; 58: Suppl. 65, PA3659.This abstract was presented at the 2021 ERS International Congress, in session “Prediction of exacerbations in patients with COPD”.This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only).