TY - JOUR T1 - Aero-allergen sensitization in a general population: data from the LEAD population cohort study JF - European Respiratory Journal JO - Eur Respir J DO - 10.1183/13993003.congress-2021.PA3114 VL - 58 IS - suppl 65 SP - PA3114 AU - Franziska Kölli AU - Marie-Kathrin Breyer AU - Sylvia Hartl AU - Gabriele Kohlböck AU - Otto Burghuber AU - Wolfgang Pohl AU - Torben Sigsgaard AU - Emiel Wouters AU - Robab Breyer-Kohansal Y1 - 2021/09/05 UR - http://erj.ersjournals.com/content/58/suppl_65/PA3114.abstract N2 - Background: Sensitization to aero-allergens is a common condition worldwide and prevalence vary between countries tremendously (17%-69%). Sensitization is related to allergic disease conditions and conflicting data of associated factors exists. Therefore, we aimed to investigate 1.the prevalence of positive SPT including age and sex distribution and 2. associated factors with positive SPT in a broad-aged European general populationMethods: 11.283 males and females aged from 6-82 yrs. from the Austrian LEAD general-population cohort have been included with aero-allergen SPT and assessments of socioeconomic status (SES), exposure to tobacco smoke, lifestyle habits, allergic and/or respiratory diseases, body composition, family medical history and pets in household.Results: Positive SPT was higher in males vs. females in both age groups (42.9% vs. 30.5% and 42.2% vs. 33.7%, p<0.05, respectively), and peak prevalence was at age 19-29 yrs.House dust mite and grasses mix were the most prevalent allergens in both age groups; however, associated factors with a positive SPT differed in the two age groups (Table1 and Table 2).Conclusion: We found that a positive SPT is a highly prevalent condition in the general population, more prevalent in males vs females, the main allergens are grasses mix and house dust mite, in both age groups. There is a difference in factors associated with SPT between childhood/adolescence and adulthood.FootnotesCite this article as: European Respiratory Journal 2021; 58: Suppl. 65, PA3114.This abstract was presented at the 2021 ERS International Congress, in session “Prediction of exacerbations in patients with COPD”.This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only). ER -