PT  - JOURNAL ARTICLE
AU  - El Wahsh, Rabab
AU  - Yousif, Maha
AU  - Ibrahim, Asmaa
TI  - Retinal vascular tortuosity in obstructive sleep apnea-COPD overlap patients
AID  - 10.1183/13993003.congress-2021.PA939
DP  - 2021 Sep 05
TA  - European Respiratory Journal
PG  - PA939
VI  - 58
IP  - suppl 65
4099  - http://erj.ersjournals.com/content/58/suppl_65/PA939.short
4100  - http://erj.ersjournals.com/content/58/suppl_65/PA939.full
SO  - Eur Respir J2021 Sep 05; 58
AB  - Background: OSA and COPD are associated with microvascular changes. Retinal microvasculature can be directly and non-invasively examined.Aim: to evaluate retinal vascular tortuosity in patients with COPD, OSA, and overlap syndrome.Subjects and method: Sixty subjects were included; 15 OSA patients, 15 COPD patients, 15 COPD-OSA overlap patients and 15 matched controls. They underwent digital retinal photography, polysomnography, arterial blood gases, spirometry, ESS and STOP-BANG questionnaires.Results: Tortuosity of most retinal vessels was higher in all patient groups compared to control group, tortuosity was more marked in overlap syndrome. There was a negative correlation between tortuosity of retinal vessels and PO2, O2 saturation and minimum O2 desaturation, and a positive correlation with PCO2, AHI, O2 desaturation index, BMI and smoking index.Conclusion: Retinal vascular tortuosity occurs in OSA, COPD and overlap syndrome. Retinal vascular tortuosity is correlated with arterial blood gases parameters, polysomnographic findings, smoking index and BMI.FootnotesCite this article as: European Respiratory Journal 2021; 58: Suppl. 65, PA939.This abstract was presented at the 2021 ERS International Congress, in session “Prediction of exacerbations in patients with COPD”.This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only).