%0 Journal Article %A Indhira Mercedes Guzman Peralta %A Luis Perez De Llano %A Eva Romay-Lema %A Adolfo Baloira Villar %A Christian Anchorena Diaz %A Maria Torres Durán %A Adrian Sousa %A Dolores Corbacho-Abelaira %A Carmen Diego-Roza %A Laura Vilariño-Maneiro %A Pedro J Marcos %A Carmen Montero Martínez %A Fernando De La Iglesia Martínez %A Vanessa Riveiro-Blanco %A Nuria Rodríguez Nuñez %A José Abal-Arca %A María Bustillo Casado %A Rafael Golpe %T COVID-19 pneumonia in Galicia (Spain): impact of prognostic factors and therapies on mortality and need for mechanical ventilation %D 2021 %R 10.1183/13993003.congress-2021.PA3808 %J European Respiratory Journal %P PA3808 %V 58 %N suppl 65 %X Introduction: This study was aimed to identify risk factors associated with unfavorable outcomes (composite outcome variable: mortality and need for mechanical ventilation) in patients hospitalized in Galicia with COVID-19 pneumonia.Methods: Retrospective, multicenter, observational study carried out in the 8 Galician tertiary hospitals. All patients admitted with confirmed COVID-19 pneumonia from 1st of March to April 24th, 2020 were included. A multivariable logistic regression analysis was performed in order to identify the relationship between risk factors, therapeutic interventions and the composite outcome variable.Results: A total of 1292 patients (56.1% male) were included. Two hundred and twenty-one (17.2%) died and 349 (27%) reached the main outcome variable. Age [odds ratio (OR) = 1.02 (95% confidence interval (CI): 1.01 – 1.03)], CRP quartiles 3 and 4 [OR = 2.06 (95% CI: 1.31 – 2.25)] and [OR = 2.76 (95% CI: 1.75 – 4.35)], respectively, Charlson index [OR = 1.17 (95%CI: 1.07 – 1.27)], SaO2 upon admission [OR = 0.94 (95% CI: 0.92 – 0.95)], the ratio admissions/hospital beds [OR = 1.05 (95% CI: 1.01 – 1.09)], hydroxychloroquine prescription [OR = 0.19 (95%CI: 0.11 – 0.33)], systemic corticosteroids prescription [OR = 2.01 (95%CI: 1.48 – 2.75)], and tocilizumab prescription [OR = 3.28 (95%CI: 2.08 – 5.17)], significantly impacted the outcome.Conclusion: These findings may help to identify patients at hospital admission with a higher risk of death and may urge healthcare authorities to implement policies aimed at reducing deaths by increasing the availability of hospital beds.FootnotesCite this article as: European Respiratory Journal 2021; 58: Suppl. 65, PA3808.This abstract was presented at the 2021 ERS International Congress, in session “Prediction of exacerbations in patients with COPD”.This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only). %U