TY - JOUR T1 - The chronic effects of narghile-use on males’ cardiovascular response during exercise: a systematic review JF - European Respiratory Journal JO - Eur Respir J DO - 10.1183/13993003.congress-2021.PA1067 VL - 58 IS - suppl 65 SP - PA1067 AU - Faten CHAIEB AU - Helmi Ben Saad Y1 - 2021/09/05 UR - http://erj.ersjournals.com/content/58/suppl_65/PA1067.abstract N2 - Introduction: Narghile-use has been regaining popularity worldwide, becoming an alarming public health. Public opinion misjudges its chronic harmful effects on health, especially on the cardiovascular system. This systematic review aimed to evaluate the chronic effects of narghile-use on cardiovascular response during exercise.Methods: This systematic review followed the preferred reporting items for systematic reviews guidelines. Original articles from Pubmed and Scopus, published until January 31st, 2020, written in English, and tackling the chronic effects of narghile-use on Human cardiovascular response during exercise were considered.Results: Five studies met the inclusion criteria. Only males were included in these studies. They were published between 2014 and 2017 by teams from Tunisia (n=4) and Jordan (n=1). One study applied the 6-min walk test and four studies opted for the cardiopulmonary exercise test. Narghile-use was associated with reduced submaximal (i.e., abnormal 6-min walk distance, and signs of walking intolerance (desaturation, dyspneoa at peak exercise)), and maximal aerobic capacities (i.e., lower maximal oxygen uptake, shorter exercise time, higher perception of leg fatigue and dyspnoea at mid exercise, and dyspnoea at peak exercise), with abnormal cardiovascular status at rest (i.e., increase in heart rate and blood pressures), at the end of the exercise (i.e., lower heart-rate, higher heart-rate reserve, and tendency to chronotropic insufficiency), and during the recovery period (i.e., lower recovery index).Conclusion: Chronic narghile-use has negative effects on cardiovascular response to exercise with reduced submaximal and maximal exercise capacities.FootnotesCite this article as: European Respiratory Journal 2021; 58: Suppl. 65, PA1067.This abstract was presented at the 2021 ERS International Congress, in session “Prediction of exacerbations in patients with COPD”.This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only). ER -