PT - JOURNAL ARTICLE AU - Alberto Braghiroli AU - Carlo Sacco AU - Andrea Giordano AU - Massimo Godio AU - Fabio Rossato AU - Sabrina Rossi AU - Sonia Carli AU - Bruno Balbi AU - David Kuller AU - Elisa Morrone TI - Validation study of a new analysis software to screen sleep respiratory disorders AID - 10.1183/13993003.congress-2021.PA2484 DP - 2021 Sep 05 TA - European Respiratory Journal PG - PA2484 VI - 58 IP - suppl 65 4099 - http://erj.ersjournals.com/content/58/suppl_65/PA2484.short 4100 - http://erj.ersjournals.com/content/58/suppl_65/PA2484.full SO - Eur Respir J2021 Sep 05; 58 AB - Introduction: The preliminary results on the reliability of Airgo™, a new screening tool for respiratory sleep disorders (RSD), prompted an improvement in software analysis to assess the occurrence and the severity of respiratory sleep disorders.Aim and objectives: To test the reliability of an improved software release in allocating patients to mild, moderate or severe obstructive sleep apnea (OSA) group vs standard cardiorespiratory monitoring (CRM).Methods: Airgo™ is an innovative device consisting of a comfortable elastic band and a small box containing a microprocessor and 3 accelerometers. It is positioned over the lower chest and calculates tidal volume and respiratory rate, detecting respiratory events during sleep and body position. We tested the device in 120 consecutive pts (21 F) simultaneously undergoing a CRM (Nox T3). The trend of AHI in the deciles 30-50% is the best descriptor of respiratory disorder.Results: The mean age of pts (± SD) is 55.7±13 yrs, BMI 27.8±4.3 kg/m2, AHI 22±22 events/hr. Airgo classified properly 27 severe OSA pts, 16 postural OSA (pOSA), 16/19 non-OSA pts (3 FP), 35/40 mild-to-moderate OSA (3 scored severe and 2 FN) and 14/16 pts (2 FN) with irregular breathing of non-OSA origin. In the OSA group the overall sensitivity is 97.5%, with 94% positive predictive value and 89% negative predictive value. The advanced visualization technique allows a refinement of analysis, correcting for false negatives and defining breathing patterns useful for phenotyping patients.Conclusions: Airgo™ is a promising screening tool to stratify the occurrence of RSD, identifying pts with severe OSA, pts with postural OSA, pts with irregular breathing and with mild-to-moderate disease.FootnotesCite this article as: European Respiratory Journal 2021; 58: Suppl. 65, PA2484.This abstract was presented at the 2021 ERS International Congress, in session “Prediction of exacerbations in patients with COPD”.This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only).