PT - JOURNAL ARTICLE AU - Alex Mcclement AU - Parag Narkhede AU - Avinash Aujayeb TI - A review of pulmonary sequestration in a district general hospital AID - 10.1183/13993003.congress-2021.PA3304 DP - 2021 Sep 05 TA - European Respiratory Journal PG - PA3304 VI - 58 IP - suppl 65 4099 - http://erj.ersjournals.com/content/58/suppl_65/PA3304.short 4100 - http://erj.ersjournals.com/content/58/suppl_65/PA3304.full SO - Eur Respir J2021 Sep 05; 58 AB - Introduction: Pulmonary sequestration (PS) is a rare congenital pulmonary malformation, often found incidentally and can cause repeated respiratory infections. Aberrant vessels from the systemic circulation provide blood supply, commonly the descending aorta. PS can be intra-lobar (ILS) {more common} or extra-lobar (ELS). Outcomes from unresected PS is unknown.Methods: With Caldicott approval, a retrospective review of all CT scans performed between 2005 and Nov 2020 for the words ‘pulmonary or lung or intra-lobar or extra-lobar sequestration’ was performed.  56,247 CTs were performed in total. 8 CTs were matched with the search words and 6 had PS. Basic demographics, clinical details and outcomes were collected. Descriptive statistical methodology was applied.Results: There were 4 male and 2 female patients. Mean age was 56.5 years (range 35-82). 3 were incidental findings and 3 were found after investigation for pain, haemoptysis and recurrent infections. 5 out of 6 were ILS and all of those were in the left lower lobe. The 1 ELS was in the right lower lobe. All had their blood supply from the descending aorta. 1 patient requested to have surgery and the ILS was excised with no complication. The 5 others did not require any intervention. 2 have died at the time of analysis due to unrelated medical issues. The incidence based on the total number of scans is 0.0084%.Conclusions: The above is a review of the incidence and outcome of PS in a large district general hospital in the North East of England. The results confirm the existing literature. We have reached out to regional hospitals so that a database can be built and encourage other centres to do the same. A crude incidence rate is 0.011% (11/100,000).FootnotesCite this article as: European Respiratory Journal 2021; 58: Suppl. 65, PA3304.This abstract was presented at the 2021 ERS International Congress, in session “Prediction of exacerbations in patients with COPD”.This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only).