PT - JOURNAL ARTICLE AU - Paola Faverio AU - Alessia Fumagalli AU - Sara Conti AU - Fabiana Madotto AU - Sara Busnelli AU - Francesco Bini AU - Sergio Harari AU - Michele Mondoni AU - Tiberio Oggionni AU - Emanuela Barisione AU - Paolo Ceruti AU - Chiara Papetti AU - Angelo De Laurentis AU - Antonella Caminati AU - Angela Valentino AU - Stefano Centanni AU - Donatella Noè AU - Matteo Della Zoppa AU - Silvia Crotti AU - Marco Grosso AU - Samir Giuseppe Sukkar AU - Denise Modina AU - Marco Andreoli AU - Roberta Nicali AU - Giulia Suigo AU - Federica De Giacomi AU - Lorenzo Giovanni Mantovani AU - Alberto Pesci AU - Fabrizio Luppi TI - Nutritional assessment in patients with idiopathic pulmonary fibrosis: the NUTRIPF study AID - 10.1183/13993003.congress-2021.PA3754 DP - 2021 Sep 05 TA - European Respiratory Journal PG - PA3754 VI - 58 IP - suppl 65 4099 - http://erj.ersjournals.com/content/58/suppl_65/PA3754.short 4100 - http://erj.ersjournals.com/content/58/suppl_65/PA3754.full SO - Eur Respir J2021 Sep 05; 58 AB - Introduction: Nutritional status (NS) impacts quality of life and prognosis of patients with respiratory diseases. The prevalence and impact of nutritional abnormalities in IPF is currently unknown.Aims: NutrIPF (NCT03770845) is a prospective multicentre study that aims to investigate the NS and to identify nutritional phenotypes in a cohort of IPF patients at the time of disease diagnosis.Methods: Pts underwent a thorough pulmonary and nutritional evaluation including questionnaires on NS and physical activity, anthropometry, body impedence (BIA), dynamometry and blood tests.Results: 90 IPF pts (79% males, mean age 72.7 yrs) were enrolled. The majority of pts were prior smokers (62, 68.9%) with an inactive lifestyle according to International Physical Activity Questionnaire (IPAQ) score (39, 43.3%) and were classified as GAP stage 2 (47, 52.2%), with mean FVC% and DLCO% 86.5 and 54.2, respectively. In regards to nutritional phenotypes, the majority of pts were normonourished (67%), followed by obese (28%), sarcopenic (5%) and sarcopenic obese (1%). The majority of normonourished patients showed early signs of nutritional and physical performance alterations including overweight in 22% of cases, history of weight loss ≥ 5% in the prior 3 months in 12% of cases, reduction of gait speed in 12% of cases and a reduction of handgrip strenght in 40% of cases. At Mini Nutritional Assessment questionnaire 18% of pts were at risk of malnutrition.Conclusions: IPF pts at baseline are mainly normonourished and obese, but early signs of nutritional alterations and physical performance impairment can already be identified at this stage and impact on nutritional and rehabilitative interventions.FootnotesCite this article as: European Respiratory Journal 2021; 58: Suppl. 65, PA3754.This abstract was presented at the 2021 ERS International Congress, in session “Prediction of exacerbations in patients with COPD”.This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only).