PT - JOURNAL ARTICLE AU - Castilho, Tayna AU - Keil, Patrícia AU - Wamosy, Renata AU - Cardoso, Juliana AU - Schivinski, Camila TI - Immediate effect of huffing on cystic fibrosis respiratory mechanics AID - 10.1183/13993003.congress-2021.PA3370 DP - 2021 Sep 05 TA - European Respiratory Journal PG - PA3370 VI - 58 IP - suppl 65 4099 - https://publications.ersnet.org//content/58/suppl_65/PA3370.short 4100 - https://publications.ersnet.org//content/58/suppl_65/PA3370.full SO - Eur Respir J2021 Sep 05; 58 AB - Background: The huffing technique (HT) is one of the interventions used by physiotherapists and individuals with cystic fibrosis (CF) to promote airway clearance, and it is an alternative to substitute coughing. However, it is necessary to investigate the repercussion of this technique on respiratory mechanics.Objectives: To investigate the immediate effect of HT on respiratory mechanics of children/adolescents with CF.Methods: a cross-sectional analytical study. There were included children/adolescents with CF between 6 to 15 years old, clinically stable. The individuals performed 5 low volume HT, followed by 3 high volume HT. The main outcomes measures were the Impulse Oscillometry System parameters evaluated pre and post the intervention. The following parameters were analyzed: impedance (Z5), total (R5) and central (R20) airway resistance, and reactance (X5), also, they were presented as absolute values and predicted percentage.Results: Participated in 43 children and adolescents, with a mean age of 10.44±2.64 years old, and mean FEV1 of 78.51±23.28%. The comparison between the pre and post-HT moments showed a significant increase in the IOS parameters after HT, which was observed in absolute values (Z5:p<0.001, R5:p<0.001, R20:p<0.001. X5:p=0.008) and in predicted percentage (Z5%:p<0.001, R5%:p<0.001, R20%:p<0.001, X5%:p=0.006).Conclusions: The HT increased the airway resistance in children/adolescents with CF, which means that immediately after the intervention the respiratory mechanics worsened. Further investigation is necessary to verify if HT leads to less increase in airway resistance than coughing.FootnotesCite this article as: European Respiratory Journal 2021; 58: Suppl. 65, PA3370.This abstract was presented at the 2021 ERS International Congress, in session “Prediction of exacerbations in patients with COPD”.This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only).