RT Journal Article SR Electronic T1 Burden of asthma by treatment step in the French CONSTANCES general population cohort JF European Respiratory Journal JO Eur Respir J FD European Respiratory Society SP PA3717 DO 10.1183/13993003.congress-2021.PA3717 VO 58 IS suppl 65 A1 Roche, Nicolas A1 Nadif, Rachel A1 Fabry-Vendrand, Caroline A1 Pillot, Laura A1 Thabut, Gabriel A1 Teissier, Clément A1 Bouée, Stéphane A1 Zins, Marie A1 Goldberg, Marcel YR 2021 UL https://publications.ersnet.org//content/58/suppl_65/PA3717.abstract AB Introduction: Data on health care consumption and costs of asthma in the French population are scarce. CONSTANCES is a prospective general population cohort involving more than 200,000 volunteers.Objective: To describe the burden of asthma in France according to GINA treatment steps.Methods: Data (medical assessment & self-questionnaires) from participants included between 2012 and 2017 were extracted and linked to the French claim and hospitalization database (SNDS). Participants were considered as current asthmatics if asthma was reported at inclusion and asthma symptoms and/or treatments were present in 2017.Results: Among 120,000 participants, 5,296 asthmatics were identified and matched with 5,296 controls. Treatment step could not be categorized for 1,556 asthmatics due to lack of any treatment dispensation. Average annual cost of outpatient care was €1,960 versus €1,362 for participants without asthma. The frequency of asthmatics with symptoms, airflow limitation, cardiovascular risk factors and co-morbidities, outpatient visits and hospitalisations increased with GINA treatment steps, as well as inpatient and outpatient costs.Conclusion: The burden of asthma can be estimated at €600 per year and per patient on average in the population and increases with GINA treatment step, as well as the burden of symptoms and comorbidities.FootnotesCite this article as: European Respiratory Journal 2021; 58: Suppl. 65, PA3717.This abstract was presented at the 2021 ERS International Congress, in session “Prediction of exacerbations in patients with COPD”.This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only).