RT Journal Article SR Electronic T1 Certain conditions of respiratory assessment affect breathing frequency and awareness JF European Respiratory Journal JO Eur Respir J FD European Respiratory Society SP PA3214 DO 10.1183/13993003.congress-2021.PA3214 VO 58 IS suppl 65 A1 Olivier Van Hove A1 Olivier Debeir A1 Vasileios Andrianopoulos A1 Dimitri Leduc A1 Gael Deboeck A1 Bruno Bonnechère YR 2021 UL http://erj.ersjournals.com/content/58/suppl_65/PA3214.abstract AB Introduction: The evaluation of breathing function may be influenced by the conditions under which it is assessed. This can be of critical importance in both clinical settings and research. This study aims to analyze the effect of different tasks on the breathing pattern.Methods: 34 healthy subjects (24±2 years, 20 women). Four conditions were assessed: 1. Rest, 2. Cognitive load (CL), 3. Inspiratory load of 15cmH20 (IL), and 4. Both combined (BC). The order of the tasks was randomly defined.  Respiratory rate (RR) was recorded during 3min under each condition with the Kinect V2®. After each session, breathing discomfort (A1 score of the Multidimensional Dyspnea Profile questionnaire) and the awareness of breathing (AB) with a 10cm AVS were assessed.Results: The RR was at 15 ±3 / min at rest and increases with the addition of CL to 19 ±3 / min (p<.001) and decreases with IL to 13 ±4 / min, (p<.01) and during BC to 13 ±4 / min, (p<.05). AB was 5.5±2.3 at rest, it decreases with CL (1.5 ± 1.74, p<.001), increases with IC (7.8 ± 2.2, p<.001) and was similar when BC (5.7±2.46, p=.86). A similar trend was observed for A1: Rest (1±0.90), CL (0.5 ± 0.9, p<.01), CI (4.8 ± 2.2, p<001) but on the other hand it increases with BC (4.9 ± 2.2). Awareness and discomfort of breathing are negatively correlated with RR (r=-0.42, p<.001 and r=-0.32, p<.001 respectively).Measurements and Main Results: Monitoring respiratory pattern by camera increases subject's awareness of breathing and can affects respiratory rate (instrumental effect). Inspiratory load increases discomfort and breathing awareness. The cognitve load does not seem to have a distractive effect on the discomfort but on the breathing awareness.FootnotesCite this article as: European Respiratory Journal 2021; 58: Suppl. 65, PA3214.This abstract was presented at the 2021 ERS International Congress, in session “Prediction of exacerbations in patients with COPD”.This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only).