RT Journal Article SR Electronic T1 Structural characteristics of a novel catheter for esophageal pressure monitoring JF European Respiratory Journal JO Eur Respir J FD European Respiratory Society SP PA3229 DO 10.1183/13993003.congress-2021.PA3229 VO 58 IS suppl 65 A1 Gabriella Abbate A1 Sebastiano Colombo A1 Keibun Liu A1 Clayton Semenzin A1 Noriko Sato A1 Carmen Ainola A1 Emily Wood A1 Davide Chiumello A1 Jacky Suen A1 Jo Pauls A1 John Fraser A1 Gianluigi Li Bassi YR 2021 UL http://erj.ersjournals.com/content/58/suppl_65/PA3229.abstract AB Introduction: Esophageal pressure monitoring allows estimation of transpulmonary pressure and precise application of lung-protective ventilation.Aims and Objectives: We describe structural characteristics of a novel esophageal catheter comprising a polyurethane balloon in comparison with commercially available alternatives.Methods: We tested a novel catheter (AspisafeNG+, Aspisafe Solution, NY, USA), designed to monitor esophageal pressure and prevent gastro-esophageal reflux vs. four commercially available catheters. We used a caliper to measure esophageal balloon outer diameter (OD) and length. Balloon compliance was measured via 0.5-mL increments of air up to an internal pressure of 40 cmH2O. Minimum volume (Vmin) was defined as the inflated volume that caused a linear increase in balloon internal pressure. Each experiment was made in triplicate.Results: Balloon OD varied among catheters (N 15, p=0.012) and ranged from median (IQR) of 6.6 (0.5) mm (Cooper®), up to 25.2 (0.2) mm (AspisafeNG+). Balloon lengths as well differed among catheters (N 15, p=0.013) from median (IQR) of 39.1 (2.5) mm (Aspisafe NG+), up to 100.7 (0.7) mm (Nutrivent®). Vmin (N 15, p=0.010) varied among catheters, as reported in Fig.1, while compliance did not (N 103, p=0.714).Measurements and Main Results: The novel esophageal balloon is characterized by large OD and Vmin. Manufacturers produce highly heterogeneous catheters for esophageal pressure monitoringFootnotesCite this article as: European Respiratory Journal 2021; 58: Suppl. 65, PA3229.This abstract was presented at the 2021 ERS International Congress, in session “Prediction of exacerbations in patients with COPD”.This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only).