TY - JOUR T1 - NOVELTY: a landmark study in phenotyping and endotyping chronic obstructive airway diseases in real clinical practice JF - European Respiratory Journal JO - Eur Respir J DO - 10.1183/13993003.00627-2021 VL - 58 IS - 3 SP - 2100627 AU - Renaud Louis AU - Gilles Louis AU - Olivier Bonhomme Y1 - 2021/09/01 UR - http://erj.ersjournals.com/content/58/3/2100627.abstract N2 - Asthma and COPD are two common chronic airway diseases associated with high morbidity and mortality [1, 2]. It is estimated that approximately 20% of asthma and COPD have diagnosis or features of both [3]. There is growing appreciation of the need to tease out phenotypes and endotypes across the spectrum of chronic airway diseases [4, 5], to evolve towards precision medicine [6, 7]. While there have been recent large cohort studies following either severe asthma [8] or COPD [9], there is paucity of large real life longitudinal studies investigating both asthma and COPD together with the asthma/COPD overlap across the all disease severity spectrum without any predetermined pharmacological intervention.NOVELTY is a prospective real life observational study that investigates asthma, COPD and asthma/COPD overlap over a period of years with the purpose to relate phenotype and endotype to clinical outcomes and disease trajectories https://bit.ly/3qERZRD ER -