TY - JOUR T1 - Human reading <em>versus</em> computer-automated reading of chest radiographs in a tuberculosis screening programme in Romania JF - European Respiratory Journal JO - Eur Respir J DO - 10.1183/13993003.04628-2020 VL - 58 IS - 1 SP - 2004628 AU - Gerard de Vries AU - Dan Gainaru AU - Sytze Keizer AU - Beatrice Mahler AU - Ileana Radulescu AU - Marina Zamfirescu AU - Ibrahim Abubakar Y1 - 2021/07/01 UR - http://erj.ersjournals.com/content/58/1/2004628.abstract N2 - One of the interventions in tuberculosis (TB) control is to screen people at high risk for TB with chest radiography [1]. Chest radiography in TB screening programmes are usually read by a radiographer or a pulmonologist specialised in TB. In recent years, computer-aided detection (CAD) software has become available for automated reading of CXRs and identifying people with presumptive TB [2, 3] and for TB screening [4, 5]. A systematic review published in 2016 concluded that the evidence of diagnostic accuracy of CAD was limited by the small number of studies, co-authored by owners of the only CAD software on the market at that time, and not generalisable to low TB and HIV settings [6]. The application of CAD software for TB detection has to our knowledge not been assessed in Europe.Automated reading of chest radiographs in a tuberculosis screening programme can reduce human reading to less than 20% of the chest radiographs, avoiding unnecessary TB examinations while maintaining high sensitivity https://bit.ly/3kCFWmqThe authors gratefully acknowledge the E-DETECT TB (709624) project which has received funding from the European Union's Health Programme (2014–2020). The views expressed here are the authors only and are their sole responsibility; it cannot be considered to reflect the views of the European Commission and/or the Consumers, Health, Agriculture and Food Executive Agency or any other body of the EU. ER -