TY - JOUR T1 - Fine particulate matter and out-of-hospital cardiac arrest of respiratory origin JF - European Respiratory Journal JO - Eur Respir J DO - 10.1183/13993003.04299-2020 VL - 57 IS - 6 SP - 2004299 AU - Sunao Kojima AU - Takehiro Michikawa AU - Kunihiko Matsui AU - Hisao Ogawa AU - Shin Yamazaki AU - Hiroshi Nitta AU - Akinori Takami AU - Kayo Ueda AU - Yoshio Tahara AU - Naohiro Yonemoto AU - Hiroshi Nonogi AU - Ken Nagao AU - Takanori Ikeda AU - Yoshio Kobayashi A2 - , Y1 - 2021/06/01 UR - http://erj.ersjournals.com/content/57/6/2004299.abstract N2 - Exposure to ambient air pollution increases mortality and is a leading contributor to the global disease burden [1]. Epidemiological studies have elucidated a relationship between out-of-hospital cardiac arrests (OHCAs) and air pollutants, especially particulate matter (diameter ≤2.5 μm; PM2.5) [2, 3]. The causes of OHCA are broadly categorised as cardiac and non-cardiac [4]. A 10 µg·m−3 increase in PM2.5 exposure yielded a 1.6% increase in the incidence of cardiac origin OHCA [3, 5]. However, few studies on OHCAs of non-cardiac origin, including intrinsic respiratory diseases (COPD/pneumonia/asthma) are available. We examined the association between short-term exposure to PM2.5 and bystander-witnessed respiratory origin OHCAs, including eventual prognosis. We also investigated differences between PM2.5 exposure-related cardiac and respiratory origin OHCAs.Particulate matter is a potential risk factor for out-of-hospital cardiac arrests (OHCAs) of respiratory origin. The percent increase in incidence of OHCA of respiratory origin is equivalent to that of PM2.5 exposure-related OHCAs of cardiac origin. http://bit.ly/3tDXym0Takashi Amano and Kanako Kojima provided administrative assistance to the Subcommittee on Resuscitation Science (Japanese Circulation Society). Staff at the Fire and Disaster Management Agency and the Institute for Fire Safety and Disaster Preparedness of Japan cooperated in establishing and maintaining the All-Japan Utstein Registry. These individuals received no additional compensation, outside of their usual salary, for their contributions. We thank the emergency medical services personnel and physicians in Japan. ER -