TY - JOUR T1 - Late Breaking Abstract - Clinical variation in presenting characteristics of COVID-19 at St George’s Hospital, London JF - European Respiratory Journal JO - Eur Respir J DO - 10.1183/13993003.congress-2020.3589 VL - 56 IS - suppl 64 SP - 3589 AU - Jessica Gates AU - Dagan Lonsdale AU - Ashwini Maudhoo AU - Ashwin Sundaram AU - Joseph Salem AU - Victoria Taylor AU - Emma Lombard AU - Hannah Gardiner AU - Natasha Benons AU - Anne Dunleavy AU - Adrian Draper AU - Yee-Ean Ong Y1 - 2020/09/07 UR - http://erj.ersjournals.com/content/56/suppl_64/3589.abstract N2 - Introduction: COVID-19 arrived as a new disease entity to the UK in early 2020. As one of the tertiary hospitals to admit COVID-19 patients, we collected data in order to characterise patientsMethod: Data was collected on 771 patients admitted with confirmed COVID-19 during the first 3 months of the pandemic, who had already been discharged or died. Presenting symptoms, co-morbidities, frailty, observations, ethnicity and mortality were noted.Results: The median age was 72 with a median clinical frailty score (CFS) and Charlson co-morbidity index (CCI) of 4. The most frequently reported symptoms were fever(62%), cough(60%) and breathlessness (57%) but older patients had more presentations with falls (34%) and confusion (37%). Older patients presented earlier compared with younger patients (2 vs 7 days). Patients with a CCI of 0 had a median age of 38 and frailty score of 2, whilst patients with CCI ≥5 had a median age of 82 and frailty score of 6. The most common co-morbidities were hypertension(42%), diabetes mellitus (31%)and chronic respiratory disease(16%). Data on ethnicity and mortality is undergoing further analysisConclusion: This is a large single site cohort of COVID-19 patients. Older patients presented sooner after symptom onset. They were more likely to present with falls and confusion and have a higher frailty score and co-morbidity index. Further multivariate analysis is ongoing to examine additional variables.FootnotesCite this article as: European Respiratory Journal 2020; 56: Suppl. 64, 3589.This abstract was presented at the 2020 ERS International Congress, in session “Respiratory viruses in the "pre COVID-19" era”.This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only). ER -