TY - JOUR T1 - The five-repetition sit-to-stand test (5STS) in patients with bronchiectasis: validity and reponsiveness JF - European Respiratory Journal JO - Eur Respir J DO - 10.1183/13993003.congress-2020.1830 VL - 56 IS - suppl 64 SP - 1830 AU - Suhani Patel AU - Ruth Barker AU - Jessica Walsh AU - Oliver Polgar AU - Claire Nolan AU - William Man Y1 - 2020/09/07 UR - http://erj.ersjournals.com/content/56/suppl_64/1830.abstract N2 - Background: The 5STS is a test of lower limb function that measures the fastest time taken to stand up and sit down from a chair five times without use of the upper limbs. It has been validated in COPD, but data in bronchiectasis is lacking.Aim: To determine the validity and responsiveness of 5STS in patients with bronchiectasis.Methods: 5STS, incremental shuttle walk test (ISW), MRC dyspnoea score (MRC), and Chronic Respiratory Questionnaire (CRQ) were measured in 133 patients with bronchiectasis before and after 8-weeks of outpatient pulmonary rehabilitation (PR).Results: Baseline characteristics and change with PR are presented in Table 1. At baseline there was a significant correlation between 5STS and MRC, ISW and CRQ-fatigue (r=0.34, -0.56, -0.23 respectively). Following PR, there were significant improvements in 5STS, ISW, CRQ-total and MRC with an effect size of 0.48, 0.55, 0.25 and 0.39 respectively. Change in 5STS with PR did not correlate with change in ISW, CRQ or MRC.Conclusion: 5STS is responsive to PR in patients with bronchiectasis with an effect size of 0.48. Change in 5STS did not correlate with changes in other outcome measures and may therefore provide additional information to traditional PR outcome measures. View this table:Table 1 Baseline characteristics and response to PRFootnotesCite this article as: European Respiratory Journal 2020; 56: Suppl. 64, 1830.This abstract was presented at the 2020 ERS International Congress, in session “Respiratory viruses in the "pre COVID-19" era”.This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only). ER -