TY - JOUR T1 - Evaluation of noncystic fibrosis bronchiectasis: six-year single center experience JF - European Respiratory Journal JO - Eur Respir J DO - 10.1183/13993003.congress-2020.1158 VL - 56 IS - suppl 64 SP - 1158 AU - FAZILCAN ZİREK AU - Gizem Özcan AU - Nazan Çobanoğlu Y1 - 2020/09/07 UR - http://erj.ersjournals.com/content/56/suppl_64/1158.abstract N2 - Introduction: Bronchiectasis is characterized by irreversible regional or diffuse dilatation and structural disruption of bronchial tree with bronchial and peribronchial destruction; that is a chronic, progressive respiratory disease accompanied by persistent cough, sputum, and recurrent pulmonary infections. In developing countries, noncystic fibrosis bronchiectasis (NCFB) are more common than bronchiectasis with cystic fibrosis. In our study, we aimed to evaluate cases with NCFB in our clinic.Methods: Medical records of patients with NCFB those were admitted to our hospital between January 2014 and January 2020 were retrospectively analyzed. The demographic and clinical features, radiological findings and prognoses of the patients were evaluated.Results: Of total 40 patients the median age of diagnosis was 13 years. Twenty-four (60%) of the patients were girls. Immunodeficiencies (32.5%) were the most common etiological condition. Respiratory function tests were performed in 29 (72,5%) patients. The mean±SD values for FVC was 77±23%, FEV1 was 74±21%, FEV1/FVC was 95±12%, FEF25-75 was 78±30% at first evaluation. Haemophilus İnfluenza was the most commonly isolated microorganism from the sputum cultures. Twenty-seven (67,5%) patients underwent flexible bronchoscopy. Medical treatment was started in 29 (72.5%) of the patients. Three (7.5%) patients underwent lobectomy. The median follow-up period of the patients was 1 year 9 months.Conclusion: NCF bronchiectasis is an emerging pediatric disease. Early diagnosis is essential to prevent a progressive decline in lung function and recurring exacerbations. Etiology is essential to improve the course of the disease by using specific threapy.FootnotesCite this article as: European Respiratory Journal 2020; 56: Suppl. 64, 1158.This abstract was presented at the 2020 ERS International Congress, in session “Respiratory viruses in the "pre COVID-19" era”.This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only). ER -