PT - JOURNAL ARTICLE AU - Dilber Ademhan Tural AU - Beste Ozsezen AU - Birce Sunman AU - Gulsen Hazırolan AU - Nagehan Emiralioglu AU - Ebru Yalcin AU - Deniz Dogru AU - Ugur Ozcelik AU - Nural Kiper TI - Clinics of Cystic Fibrosis Patients with Unusual Bacteria Isolated fromRespiratory Cultures AID - 10.1183/13993003.congress-2020.687 DP - 2020 Sep 07 TA - European Respiratory Journal PG - 687 VI - 56 IP - suppl 64 4099 - http://erj.ersjournals.com/content/56/suppl_64/687.short 4100 - http://erj.ersjournals.com/content/56/suppl_64/687.full SO - Eur Respir J2020 Sep 07; 56 AB - Objectives-Aim:Unusual bacteria(UB) have been described by new isolation techniques recently which are not typed as P. aeruginosa,S. aureus, H. influenzae, and Burkholderia cepacia complex organisms.The aim is to investigate the effects of the presence of UB in the respiratory culture of CF patients on clinical outcomes, necessity of treatment and on prognosis.Methods: The UB were identified by MALDI-TOF(matrix-assisted laser desorption/ionisation time of-flight) mass spectrometry technology.Results: Rhizobium radiobacter were detected in 2 patients,Chyrseobacterium species (gleum and indolgenes) in 5, Aeromonas hydrophila in 1,Orchobacterium anthropy in 1,Wautersiella falsenii in 1,Leclercia adecarboxylata in 1,Delftia acidovorans in 1,Cupriavidus Gilardi in1,Rhizobium radiobacter twith Elizabethkingia miricola in 1 and Rhizobium radiobacter with Chyrseobacterium gleum in 1 patient. Median age of the first UB growth was 3 years old. After the first UB growth the median followup time was 15 months. Before the UB growth, %60.0 patients had respiratory colonization with methicillin-susceptible S. aureus(MSSA) and UB growth were accompanied with MSSA in %66.6 patients. Median percentage of FEV1 before and during the UB growth who could perform spirometry, were 80 and 102, resp. Median body mass index (BMI) before and during the UB growth were 16 and 16.2,respectively. These UB were not detected during the followups except in one patient who had intermittent Rhizobium radiobacter growth.Conclusion: Our study showed that UB growth did not cause any additional symptoms and change in BMI and FEV1. MSSA may be a facilitating factor for these UB growth which majority of patients had MSSA colonization.FootnotesCite this article as: European Respiratory Journal 2020; 56: Suppl. 64, 687.This abstract was presented at the 2020 ERS International Congress, in session “Respiratory viruses in the "pre COVID-19" era”.This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only).