RT Journal Article
SR Electronic
T1 Follow-up of children after resection for congenital thoracic malformations
JF European Respiratory Journal
JO Eur Respir J
FD European Respiratory Society
SP 3521
DO 10.1183/13993003.congress-2020.3521
VO 56
IS suppl 64
A1 Emma Longoni
A1 Giulia Maria Luisa Cammi
A1 Laura Paradiso
A1 Michele Ghezzi
A1 Marco Morelli
A1 Andrea Farolfi
A1 Enza Carmina D'Auria
A1 Gianvincenzo Zuccotti
YR 2020
UL http://erj.ersjournals.com/content/56/suppl_64/3521.abstract
AB We retrospectively analyzed complications and long-term pulmonary function test (PFT) in 115 children with congenital thoracic malformations after pulmonary resection.Congenital pulmonary airway malformationwas found in 40% of patients, pulmonary sequestration in 25%, congenital lobar emphysema in 10%, bronchial atresia in 4%, complex malformations in 9%, others in 10%. The most frequent type of resection was lobectomy (66%), followed by wedge resection (15.6%), segmentectomy (8.7%), pneumonectomy (4.3%). Average age at surgery was 21 months. 41.8% of patients had symptoms before surgery (16% respiratory distress, 8% pneumothorax, 7% recurrent pulmonary infections).In our series 76% of children reported long-term complications such as cough, recurrent infections, wheezing, low effort tolerance, mild scoliosis, pectus excavatum, chest X-ray abnormalities, postpneumonectomy syndrome.Nevertheless these were not statistically correlated with surgery before or after 6 months and thoracoscopy vs thoracothomy, but they were associated with segmentectomy (p-value 0.043) and not with lobectomy.We also evaluated PFT after surgery in 86/115 children at average age of 9.7 years. Restrictive pattern was found in 20%, obstructive deficit in 13%. Resection after 6 months was correlated with restrictive pattern (p-value 0.047).The lung has some capacity to organize a catch-up growth with alveolarization during childhood, for this reason we found no differences in PFT between health children and resected ones, as described in literature. Most of them enter adult life with normal PFT;but at the same time, later resections could not be completely compensated by pulmonary catch-up growth.FootnotesCite this article as: European Respiratory Journal 2020; 56: Suppl. 64, 3521.This abstract was presented at the 2020 ERS International Congress, in session “Respiratory viruses in the "pre COVID-19" era”.This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only).