RT Journal Article
SR Electronic
T1 PLEURO-PULMONARY COMPLICATIONS IN PATIENTS WITH CYSTIC FIBROSIS
JF European Respiratory Journal
JO Eur Respir J
FD European Respiratory Society
SP 2773
DO 10.1183/13993003.congress-2020.2773
VO 56
IS suppl 64
A1 Ludmila Balanetchi
A1 Rodica Selevestru
A1 Eva Gudumac
A1 Svetlana Sciuca
YR 2020
UL http://erj.ersjournals.com/content/56/suppl_64/2773.abstract
AB Introduction: The most severe clinical forms with major risks of pleuropulmonary complications are in association with multidrogresistant germs, which contribute to accelerate the destructive processes of the pulmonary parenchyma.Aim: Evaluation of pleural and pulmonary complications in CF patients with lung infections in relation with its bacterial etiology.Methods: The study includes 80 patients with CF, who was examined for microbiological analyses of the sputum and the imaging pulmonary exam, which included pulmonary radiography, computed tomography with angiography.Results: The predominate germs in patients who developed the pleuro-pulmonary complications was Ps.aeruginosa (62.5%), S.aureus (55%), St.maltophilia, B.cepacia complex.During surveillance, 25% CF patients with lung infections were diagnosed with pleurisy, which required thoracentesis in 8,7% of cases. Lung empyema was confirmed in 7,5% of cases. Pulmonary destructions (27,5% cases) developed in CF patients with exacerbations of S.aureus lung infections, Ps.aeruginosa and B.cepacia.17,5% of CF patients develop pneumothorax, which occurs as a result of pulmonary tissue rupture, which had a death rate of 11,2%, at 10-22 years of age.Conclusions: Pulmonary syndromes in patients with cystic fibrosis evolve progressively, with the risk of death by severe pleuro-pulmonary complications, which are caused by aggressive Ps.aeruginosa infections, by pulmonary alveolar affection, abscesses, atelectasis, pleurisy. The prognosis of CF with bronchopulmonary involvement is related to the degree of respiratory lesions, the character of pleuro-pulmonary complications and the presence of extrapulmonary syndromes.FootnotesCite this article as: European Respiratory Journal 2020; 56: Suppl. 64, 2773.This abstract was presented at the 2020 ERS International Congress, in session “Respiratory viruses in the "pre COVID-19" era”.This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only).