RT Journal Article SR Electronic T1 Rate of respiratory symptoms in naïve patients with Chronic lymphocytic leukemia JF European Respiratory Journal JO Eur Respir J FD European Respiratory Society SP 1913 DO 10.1183/13993003.congress-2020.1913 VO 56 IS suppl 64 A1 Gashynova, Kateryna A1 Usenko, Ganna YR 2020 UL http://erj.ersjournals.com/content/56/suppl_64/1913.abstract AB Objective: to evaluate the rate of respiratory symptoms (RS) in patients (pts) with Chronic Lymphocytic Leukemia (CLL) and its dependence on anemia, ischemic heart disease (IHD), respiratory diseases, smoking status.Materials and Methods: Retrospective analysis of medical records of pts’ with confirmed CLL who did not receive any treatment. RS (dyspnea, cough, sputum), comorbidity, smoking status were assessed. Parametric and nonparametric statistics were used for the results analysis.Results: 264 medical records of the pts with CLL who were hospitalized to Dnipro City Hematology Department in 2018 were evaluated. 46 medical records were included on final analysis (35 (76 %) men, age 64.0 (57.0;69.0) years). 8 (17.4%) of pts had dyspnea, 2 (4.3%) – dyspnea and cough, no one had sputum, 36 (78.3%) pts had no RS. According to presence of respiratory symptoms we divided the pts in two groups. Connection of respiratory symptoms with comorbidities and smoking status is present in table. 1 View this table:There were not any additional investigations of respiratory system performed despite the presence of symptoms.Conclusions: 21.7 % of naïve pts with CLL had respiratory symptoms which did not associate with comorbid anemia, CLL, respiratory diseases or smoking status. Pts with CLL and RS require more precise examination of respiratory system (spirometry, sputum test and etc.) before the initiation of treatment.FootnotesCite this article as: European Respiratory Journal 2020; 56: Suppl. 64, 1913.This abstract was presented at the 2020 ERS International Congress, in session “Respiratory viruses in the "pre COVID-19" era”.This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only).