PT  - JOURNAL ARTICLE
AU  - Maria Morales Gonzalez
AU  - Cayo García Polo
AU  - Carolina España Domínguez
AU  - Isabel Muñoz Ramírez
AU  - María Pérez Morales
TI  - Negative predictive value of EBUS-TBNA in mediastinal staging of lung cancer
AID  - 10.1183/13993003.congress-2020.3477
DP  - 2020 Sep 07
TA  - European Respiratory Journal
PG  - 3477
VI  - 56
IP  - suppl 64
4099  - http://erj.ersjournals.com/content/56/suppl_64/3477.short
4100  - http://erj.ersjournals.com/content/56/suppl_64/3477.full
SO  - Eur Respir J2020 Sep 07; 56
AB  - Introduction: It remains unclear whether surgical staging by mediastinoscopy, VATS or open surgery is always necessary after a negative result of EBUS-TBNA. The objective of this study is to determine the negative predictive value (NPV) of EBUS-TBNA for mediastinal staging of lung cancer.Methods: Retrospective analysis of patients undergoing EBUS-TBNA, for pre-operative mediastinal staging of lung cancer, in the period from February 2016 to September 2019.Results: Of a total of 453 examinations in the referred study period, 56 patients met the study criteria. The average age was 66 years (48-80), and 51 cases (91.1%) were men. A total of 118 punctures of mediastinal adenopathies were perdormed, with a mean of 3.46 passes for adenopathy. Puncture adenopathies were 7 (n =40), 4R (n = 33); 4L (n = 16), 10R (n = 9), 2R (n = 7), 11R (n = 5), 11L (n = 4), 10L (n = 3) and 8 (n= 1). Clot was obtained in 66.9% of punctures (n = 79). The needle size was 19G (n = 1), 21G (n = 18), 22G (n = 9) and not recorded in 28 cases. The definitive surgical technique for staging was mediastinoscopy (n = 8), VATS (n = 12) or open surgical resection (n = 41). The overall negative predictive value of EBUS-TBNA was 92.9% with false negatives in 4 patients.Conclusions: EBUS-TBNA has a high NPV in mediastinal staging of lung cancer, confirming that this endoscopic technique is safe and effective in the preoperative staging of non-small cell lung cancer. Depending on the results presented, it is posible that EBUS-TBNA negative mediastinal lymph nodes do not need surgical confirmation.FootnotesCite this article as: European Respiratory Journal 2020; 56: Suppl. 64, 3477.This abstract was presented at the 2020 ERS International Congress, in session “Respiratory viruses in the "pre COVID-19" era”.This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only).