RT Journal Article
SR Electronic
T1 Using the Rox index for Nasal High Flow therapy in patients with interstitial lung disease and severe acute respiratory failure
JF European Respiratory Journal
JO Eur Respir J
FD European Respiratory Society
SP 3446
DO 10.1183/13993003.congress-2020.3446
VO 56
IS suppl 64
A1 Ana Cysneiros
A1 Diana Organista
A1 Daniela Machado
A1 Daniela Rodrigues
A1 Francisca Lopes
A1 Catarina Antunes
A1 Fernanda Paula
A1 Filipe Froes
YR 2020
UL http://erj.ersjournals.com/content/56/suppl_64/3446.abstract
AB Background: The ROX index, defined as the ratio of SpO2/FIO2 to respiratory rate is used to predict outcome of Nasal High Flow Cannula therapy (HFNC). ROX score greater than or equal to 4.88 measured at 12 hours predicts lower risk of progressing to mechanical ventilation. Patients with Interstitial Lung Disease (ILD) and Severe Acute Respiratory Failure (SARF) defined as P/F ratio ≤ 200 have very poor prognosis and are usually not suitable for invasive mechanical ventilation hence HFNC is frequently defined as ceiling of care since.Objectives: To assess the use of the ROX index in patients with ILD and SARFMethods: Single centre retrospective analysis of adult patients with ILD and SARF admitted to a Intensive Care between 2014 and 2019Results: There where twelve patients with different ILD admitted between 2014 and 2019. Mean age was 58.3 (Min 20; Max 79), eight where male and five where current or ex-smokers. The ROX score was above 4.88 at 12 hours for all but three patients. These were the only patients who were discharged alive from intensive care.Conclusion: Despite the small sample size the ROX index might be useful in predicting success with HFNC in patients with ILDFootnotesCite this article as: European Respiratory Journal 2020; 56: Suppl. 64, 3446.This abstract was presented at the 2020 ERS International Congress, in session “Respiratory viruses in the "pre COVID-19" era”.This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only).