PT  - JOURNAL ARTICLE
AU  - Ana Cysneiros
AU  - Diana Organista
AU  - Daniela Machado
AU  - Daniela Rodrigues
AU  - Francisca Lopes
AU  - Catarina Antunes
AU  - Fernanda Paula
AU  - Filipe Froes
TI  - Using the Rox index for Nasal High Flow therapy in patients with interstitial lung disease and severe acute respiratory failure
AID  - 10.1183/13993003.congress-2020.3446
DP  - 2020 Sep 07
TA  - European Respiratory Journal
PG  - 3446
VI  - 56
IP  - suppl 64
4099  - http://erj.ersjournals.com/content/56/suppl_64/3446.short
4100  - http://erj.ersjournals.com/content/56/suppl_64/3446.full
SO  - Eur Respir J2020 Sep 07; 56
AB  - Background: The ROX index, defined as the ratio of SpO2/FIO2 to respiratory rate is used to predict outcome of Nasal High Flow Cannula therapy (HFNC). ROX score greater than or equal to 4.88 measured at 12 hours predicts lower risk of progressing to mechanical ventilation. Patients with Interstitial Lung Disease (ILD) and Severe Acute Respiratory Failure (SARF) defined as P/F ratio ≤ 200 have very poor prognosis and are usually not suitable for invasive mechanical ventilation hence HFNC is frequently defined as ceiling of care since.Objectives: To assess the use of the ROX index in patients with ILD and SARFMethods: Single centre retrospective analysis of adult patients with ILD and SARF admitted to a Intensive Care between 2014 and 2019Results: There where twelve patients with different ILD admitted between 2014 and 2019. Mean age was 58.3 (Min 20; Max 79), eight where male and five where current or ex-smokers. The ROX score was above 4.88 at 12 hours for all but three patients. These were the only patients who were discharged alive from intensive care.Conclusion: Despite the small sample size the ROX index might be useful in predicting success with HFNC in patients with ILDFootnotesCite this article as: European Respiratory Journal 2020; 56: Suppl. 64, 3446.This abstract was presented at the 2020 ERS International Congress, in session “Respiratory viruses in the "pre COVID-19" era”.This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only).