PT  - JOURNAL ARTICLE
AU  - Stella, Giulia Maria
AU  - Valizia, Claudio
AU  - Saracino, Laura
AU  - Agustoni, Francesco
AU  - Pozzi, Emma
AU  - Rinaldi, Pietro
AU  - Primiceri, Cristiano
AU  - Bosio, Matteo
AU  - Morbini, Patrizia
AU  - Bortolotto, Chandra
AU  - Corsico, Angelo
TI  - Multidisciplinary Approach in the Evaluation and Management of Patients with Malignant Pleural Mesothelioma. A Single Center Experience
AID  - 10.1183/13993003.congress-2020.1139
DP  - 2020 Sep 07
TA  - European Respiratory Journal
PG  - 1139
VI  - 56
IP  - suppl 64
4099  - https://publications.ersnet.org//content/56/suppl_64/1139.short
4100  - https://publications.ersnet.org//content/56/suppl_64/1139.full
SO  - Eur Respir J2020 Sep 07; 56
AB  - Malignant Pleural Mesothelioma (MPM) is an aggressive cancer with very dismal prognosis whose pathogenesis is mainly associated with exposure to asbestos fibers. Although recognized as a rare disease, in Italy MPM has a very high incidence due the past presence of asbestos cement factories and is a medical priority. At our Institution a dedicated integrated path to diagnose and assist patients affected by MPM has been activated since 2017. A total of 88 patients were analyzed, 61 males and 27 females, respectively. Most cases arrived from the province of Pavia (74.84%),. The mean age at diagnosis was 69.7 years, overall survival 14.2 months. Exhaustive epidemiologic and clinical data are detailed in Fig. 1. Each case was discussed by a multidisciplinary group to a proper therapeutic multimodal treatment, encopasses first line chemo (platinum/pemetrexed) and/or pleurectomy. Radiotherapy was limited to palliation of pain. Notably, we compared the use of gemcitabine vs navelbine as second line approach in case of disease progression and no statistical differences (p<0.0001) was observed in patient outcome in the cohort analyzed.Malignant FootnotesCite this article as: European Respiratory Journal 2020; 56: Suppl. 64, 1139.This abstract was presented at the 2020 ERS International Congress, in session “Respiratory viruses in the "pre COVID-19" era”.This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only).