PT  - JOURNAL ARTICLE
AU  - Elena Zhekaite
AU  - Elena Kondratyeva
AU  - Anna Voronkova
AU  - Viktoria Sherman
AU  - Roman Budzinsky
AU  - Aisa Zodbinova
AU  - Yulia Melyanovskaya
TI  - Vitamin D status correlates with lung function in children and adolescents with cystic fibrosis
AID  - 10.1183/13993003.congress-2020.366
DP  - 2020 Sep 07
TA  - European Respiratory Journal
PG  - 366
VI  - 56
IP  - suppl 64
4099  - http://erj.ersjournals.com/content/56/suppl_64/366.short
4100  - http://erj.ersjournals.com/content/56/suppl_64/366.full
SO  - Eur Respir J2020 Sep 07; 56
AB  - The aim: to examine whether vitamin D status correlates with lung function in children and adolescents with cystic fibrosis (CF).Method: 150 measurements of serum vitamin D level were made, followed by spirometry in patients with CF 6-18 years old. Serum 25(OH)D was evaluated using ELISA. Spirometry was performed on an Easy on-PC device (and Medical Technologies, Zurich, Switzerland) and was considered normal with FVC ≥80% and FEV1 ≥80%.Results: The average level of 25(OH)D differed significantly. in patient with FVC>80% it was 31.9ng\ml, in patient with FVC<80% - 21.4ng\ml (p=0.02). The average level of 25(OH)D in patient with FEV1>80% was 32.3ng\ml, in patient with FEV1<80% - 26.7ng\ml (p=0.01). The frequency of vitamin D deficiency (defined by < 20 ng/ml) in patients with FVC<80% was higher than that in patients with FVC<80% - 46.2% and 17.5%, respectively (p<0.014).The frequency of vitamin D deficiency in patients with FEV1<80% was 44.8%, in patients with FEV1>80% - 14.0% (p<0.001).Method: Vitamin D status correlates with lung function in patients with CF. Vitamin D deficiency is more common in patients with lower FVC and FEV1.FootnotesCite this article as: European Respiratory Journal 2020; 56: Suppl. 64, 366.This abstract was presented at the 2020 ERS International Congress, in session “Respiratory viruses in the "pre COVID-19" era”.This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only).