RT Journal Article
SR Electronic
T1 Mycobacterial non-tuberculosis infection in patients operated on for pulmonary tuberculosis
JF European Respiratory Journal
JO Eur Respir J
FD European Respiratory Society
SP 1704
DO 10.1183/13993003.congress-2020.1704
VO 56
IS suppl 64
A1 Vilayat Aliev
A1 Larisa Lepeha
A1 Elena Krasnikova
A1 Tatyana Smirnova
A1 Svetlana Sadovnikova
A1 Mamad Bagirov
YR 2020
UL http://erj.ersjournals.com/content/56/suppl_64/1704.abstract
AB Introduction: Non-tuberculous mycobacteriosis (NTM) can be accompanied by the formation of focal lesions and destructive cavities in the lungs. In the absence of bacterial excretion, these patients require differential diagnosis with pulmonary tuberculosis.Aim: Study of the effectiveness of surgery for the differential diagnosis and treatment of patients with NTM.Methods: A retrospective analysis of 68 cases of detection of NTM in patients underwent surgery for suspected tuberculosis in the 5 years period was performed. The features of the clinical course of the disease, the X-ray pattern, perioperative management, as well as the characteristic of the morphological picture of NTM in the pulmonary parenchyma was studied.Results: All patients were admitted to the hospital due to ineffective TB therapy or for verification of the diagnosis. According to X-ray pattern before surgery, these processes were regarded as fibro-cavernous - 20, cavernous - 13, tuberculomas - 29, cirrhotic tuberculosis - 6. Surgical interventions of the following volume were performed: pneumonectomy - 3, lobectomy - 12, lung resection - 54. In the lung resection material of patients, mainly slowly growing NTM were revealed. A hysthological study showed high active processes of fibrotization in the background of granulomas without necrosis. No recurrences of mycobacterial infection were reveled after surgery during the observation period.Conclusion: The introduced cases demonstrate the difficulty of differential diagnosis for pulmonary tuberculosis and non-tuberculous mycobacteriosis, and determine indications for surgery.FootnotesCite this article as: European Respiratory Journal 2020; 56: Suppl. 64, 1704.This abstract was presented at the 2020 ERS International Congress, in session “Respiratory viruses in the "pre COVID-19" era”.This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only).