RT Journal Article SR Electronic T1 Lung expansion and alternation of low attenuation volume in lobectomized patients JF European Respiratory Journal JO Eur Respir J FD European Respiratory Society SP 3129 DO 10.1183/13993003.congress-2020.3129 VO 56 IS suppl 64 A1 Masanori Yokoba A1 Tsuyoshi Ichikawa A1 Shinya Harada A1 Takahiro Ozawa A1 Seiichiro Kusuhara A1 Tomoya Fukui A1 Satoshi Igawa A1 Hisashi Mitsufuji A1 Masaru Kubota A1 Jiichiro Sasaki A1 Katsuhiko Naoki A1 Yukitoshi Sato A1 Masato Katagiri YR 2020 UL http://erj.ersjournals.com/content/56/suppl_64/3129.abstract AB Introduction: Lung expansion after lobectomy is different according to the resected lobe (Sengul AT, et al. 2013). We have reported that the percent predicted diffusing capacity of the lung for carbon monoxide (%DLco) was improved from 3 to 12 months after single lobectomy in right upper and lower lobe lobectomy (from 98.71% to 106.83% and from 84.84% to 94.49%, respectively) (Yokoba M, et al. ERS 2017). However, it is still unclear that alternation of the emphysematous lung parenchyma of ipsi- and contralateral remained lobes according to resected lobe.Purpose and Methods: The aim of this study was to prospectively compare the alternation of volume and emphysematous lung volume (low attenuation volume (LAV) on CT image defined with -950HU) of remained lobes after lobectomy. (Ethics # B13-110). The volume and LAV of each lobe were measured preoperatively (po) and 12 months (12M) postoperatively in 56 patients underwent video-assisted thoracic surgery (VATS) lobectomy.Results: Lobectomy on right upper and lower lobe (RUL and RLL) and left upper and lower lobe (LUL and LLL) were 18, 5, 15 and 8 patients, respectively.In RUL and LUL lobectomy, larger remaining ipsilateral lung expansion and minor volume increasing of the contralateral lung was shown. Alteration of %LAV of the remained lobe between 12M and po were from -0.96 to 1.39%.Conclusion: We conclude that for single VATS lobectomy, 1-year improvement of %DLco might be related with remained lobe expansion, not alternation of LAV.FootnotesCite this article as: European Respiratory Journal 2020; 56: Suppl. 64, 3129.This abstract was presented at the 2020 ERS International Congress, in session “Respiratory viruses in the "pre COVID-19" era”.This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only).