TY - JOUR T1 - Risk factors of reintubation in patients receiving post-extubation nasal high flow therapy JF - European Respiratory Journal JO - Eur Respir J DO - 10.1183/13993003.congress-2020.3447 VL - 56 IS - suppl 64 SP - 3447 AU - Min Ju Jo AU - Yun Jung Huh AU - Yoomi Yeo AU - Ji-Yong Moon AU - Tae-Hyung Kim AU - Sung Jun Chung AU - Hyun Lee AU - Dong Won Park AU - Sang Heon Kim AU - Jang Won Sohn AU - Ho Joo Yoon AU - Tai Sun Park Y1 - 2020/09/07 UR - http://erj.ersjournals.com/content/56/suppl_64/3447.abstract N2 - Background: Use of nasal high-low therapy (NHF) after extubation was known to lower reintubation rate. However, there are still patients undergoing reintubation despite of post-extubation NHF therapy.Objectives: The purpose of this study was to evaluate the risk factors of reintubation in patients receiving post-extubation NHF therapy.Methods: From January 2018 to June 2019, patients who underwent mechanical ventilation and NHF after extubation at Hanyang University Guri Hospital were analyzed retrospectively. All patients received adequate sedation and planned extubation was performed after passing spontaneous awakening test and spontaneous breathing test (SBT).Result: Total 65 patients were enrolled, mean age of the 65 patients was 71.0 [55.0;76.0] years, two thirds of patients were male and mean body mass index was 23.1 [21.1;26.0]. 10 (15.4%) patients were reintubated duration of ICU stay, which mean period was 6 days. As analyzed between reintubated Vs. non-reintubated group, there was no significant differenced between two groups in not only baseline characteristics but also use of medication or SBT duration. In clinical outcomes, duration of ICU stay in reintubated patients was significant longer, 19.0 [11.0;25.0] days (5.0 [ 4.0; 9.0] days in non-reintubated patients, p < 0.001). However, both in univariate and multivariate analysis, we cannot find significant prognostic factor.Conclusion: This was the preliminary study, there was no significant factor between two groups in prognosis. Further evaluation of risk factors of reintubation should be studied in future.FootnotesCite this article as: European Respiratory Journal 2020; 56: Suppl. 64, 3447.This abstract was presented at the 2020 ERS International Congress, in session “Respiratory viruses in the "pre COVID-19" era”.This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only). ER -