PT  - JOURNAL ARTICLE
AU  - Beatriz Abascal Bolado
AU  - Laura Sanchez Moreno
AU  - Teresa Diaz De Teran Lopez
AU  - Pablo Lozano Cuesta
AU  - Victoria Maderuelo Garcia
AU  - Claudia Loidi Lopez
TI  - Prgnostic factors in lung cancer: is preoperative Geriatric Nutritional Risk Index an independent predictive factor?
AID  - 10.1183/13993003.congress-2020.1729
DP  - 2020 Sep 07
TA  - European Respiratory Journal
PG  - 1729
VI  - 56
IP  - suppl 64
4099  - http://erj.ersjournals.com/content/56/suppl_64/1729.short
4100  - http://erj.ersjournals.com/content/56/suppl_64/1729.full
SO  - Eur Respir J2020 Sep 07; 56
AB  - The correlation between nutritional status and survival in patient with organ malignancies, including lung cancer, is well done. Previous studies supported the use of the Geriatric Nutritional Risk Index (GNRI) as a survival prognostic factor due to the significant association with nutritional parameters and both, short and long-term outcomes.The main aim of this study is to evaluate the GNRI as an independent prognostic factor of survival in geriatric patients with lung cancer who underwent pulmonary resection.Methods: Retrospective study (2010-2018) that included geriatric patients (>65 years) with major elective pulmonary resection for lung cancer. Clinical characteristics, management and outcomes were colleted. The GNRI score was calculated as 1.487 serum albumin concentration (g/L) + 41.7 preoperative body weight/ideal body weight (kg). Patients were divided in group A (GNRI>98) and grupo B (≤98), this group was at risk of malnutrition. Univariate survival analysis was undertaken using the log-rank test. Cox regression multivariate analysis was carried out accounting for different variables.Results: 341 patients were included, 326 in Group A and 15 in group B. There weren´t differences in ECOG status, gender, BMI, age, Charlson score or previous adjuvant treatment (chemotherapy or radiotherapy). Univariate and multivarate analysis didnot show statistically significant differences in survival by GNRI group (p 0.296, p 0.965 respectively).Conclusions: GNRI isnot an independent predictive factor for survival in our cohort. However, sample size, specially in group at greatest risk of malnutrition could explain our results.FootnotesCite this article as: European Respiratory Journal 2020; 56: Suppl. 64, 1729.This abstract was presented at the 2020 ERS International Congress, in session “Respiratory viruses in the "pre COVID-19" era”.This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only).