@article {Nesterovska3077, author = {Olga Nesterovska and Ganna Stupnytska and Oleksandr Fediv and Oksana Pritulyak and Iryna Nemish}, title = {An Evaluation of Slow Vital Capacity and Forced Vital Capacity Difference in Aco Patients with Obesity}, volume = {56}, number = {suppl 64}, elocation-id = {3077}, year = {2020}, doi = {10.1183/13993003.congress-2020.3077}, publisher = {European Respiratory Society}, abstract = {While COPD is characterised by an accelerated, although variable FEV1 decline , many ACO patients experience a slow decline in lung function. Among subjects with ACO, FEV1/FVC ratio may miss airflow limitation. It remains unclear whether using SVC instead of FVC increases the detecting of airflow limitation in ACO patients with obesity.Objectives: To investigate the differences between SVC and FVC in ACO patients with obesity.Methods: Subjects (n=255) aged 50{\textendash}64 years were investigated with FEV1, FVC, and SVC . All spirometric maneuvers were performed before and 15 minutes after inhalation of 400 μg of salbutamol. The 2005 ATS / ERS recommendations were used to evaluate the spirometric results.Results: The main demographic indicators of the study cohort included 68\% of men and 32\% of women, with an average age of 58.7 years. The 23.4\% of patients had preserved or mildly reduced obstruction, 38.7\% moderate, 26.75\%- severe and 11.2\% had very severe obstruction . The most subjects diagnosed with airflow obstruction according to FEV1/ SVC only had mildly reduced FEV1. Among people with normal spirometry,22,4\% had a SVC-FVC difference of more than 500 ml. Patients with BMI \> 30 kg/m2 were associated with airflow obstruction diagnosed only by FEV1/ SVC.Conclusions: Our research demonstrates great differences between FVC and SVC values . There is a greater difference between these indicators in subjects with preserved or mild obstruction This indicates that FEV1/SVC relation is the most reliable in the detection of an obstruction in ACO patients with obesity.FootnotesCite this article as: European Respiratory Journal 2020; 56: Suppl. 64, 3077.This abstract was presented at the 2020 ERS International Congress, in session {\textquotedblleft}Respiratory viruses in the "pre COVID-19" era{\textquotedblright}.This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only).}, issn = {0903-1936}, URL = {https://erj.ersjournals.com/content/56/suppl_64/3077}, eprint = {https://erj.ersjournals.com/content}, journal = {European Respiratory Journal} }