RT Journal Article SR Electronic T1 Surgical treatment of primary chest wall sarcomas: experiences in 19 cases JF European Respiratory Journal JO Eur Respir J FD European Respiratory Society SP 3131 DO 10.1183/13993003.congress-2020.3131 VO 56 IS suppl 64 A1 Mahdi Abdennadher A1 Aymen Ben Ayed A1 Amina Abdelkbir A1 Hazem Zribi A1 Sarra Zairi A1 Imen Bouassida A1 Mouna Mlika A1 Imen Sahnoun A1 Sonia Ouerghi A1 Adel Marghli YR 2020 UL http://erj.ersjournals.com/content/56/suppl_64/3131.abstract AB Introduction: Chest wall sarcomas are rare and agressive with late discovery. It rises many challenges for the confirmation of the primitive character and for the therapeutic strategy. The prognosis depends on surgical resection and histological type.Our aim was to clarify the outcomes of patients managed surgically.Methods: We retrospectively reviewed the clinical data from patients who were operated for chest wall sarcomas within 16 years at the thoracic surgery department of AbderrahmenMami Hospital Ariana–Tunisia.Results: Nineteen patients underwent resection of chest wall sarcomas. The median size of the tumor was 77.4 mm (17 to 150 mm). Eight patients received neoadjuvant chemotherapy. Elective approach was used in 14 cases. The involved rib was resected in 17 cases (1 to 4 ribs). Rib resection was extended to the diaphragm in 5 cases, the involved lung in 6 cases and the sternum in 2 cases. The chest wall defect was covered by muscular flap in 7 cases. Definitive pathological study confirmed the primitive character of sarcomas and revealed: Ewing sarcoma (6 cases), leiomyosarcoma (5 cases), synovial sarcoma (3 cases), pleomorphic sarcoma (1 case), phyllode sarcoma (1 case), chondrosarcoma (1 case),rhabdomyosarcoma(1 case) and liposarcoma(1 case).The postoperative course was complicated in 2 cases. Negative margin resection was achieved in 17 cases.Four patients received adjuvant chemotherapy.With a median follow-up of 12 months (1 – 36 months),tumor progression was observed in 4 patientsConclusion: Treatment decision for primary chest wall sarcomas should be taken in a multidisciplinary meeting. Surgical resection is associated with a good long-term outcomes. Adjuvant treatment remains a controversial issueFootnotesCite this article as: European Respiratory Journal 2020; 56: Suppl. 64, 3131.This abstract was presented at the 2020 ERS International Congress, in session “Respiratory viruses in the "pre COVID-19" era”.This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only).