TY - JOUR T1 - Ten-year review of congenital thoracic malformations in Wales JF - European Respiratory Journal JO - Eur Respir J DO - 10.1183/13993003.congress-2020.2826 VL - 56 IS - suppl 64 SP - 2826 AU - Laura Price AU - Emily King AU - Elisabeth Parks AU - Rhian Isaac AU - Iolo Doull AU - Julian Forton AU - Lena Thia Y1 - 2020/09/07 UR - http://erj.ersjournals.com/content/56/suppl_64/2826.abstract N2 - Introduction: Congenital thoracic malformations (CTM) are increasingly detected through antenatal screening but there is no universal guidance on the management of small asymptomatic lesions. All infants with antenatally detected CTM will have a chest computed tomography (CT) by 3m of age at the Children's Hospital for Wales.Aim: To evaluate the management and outcome of CTM detected antenatally and postnatally in the last 10 years.Methods: All infants with chest CT performed under one year of age from 2010-2019 were identified through specific search criteria related to CTM. CT findings and clinical management and outcomes were obtained from clinical record.Results: 79 infants (41females, 38males) were identified with CTM. 6 were diagnosed postnatally due to respiratory symptoms of which 5 required surgery (1 was a bronchopulmonary sequestration (BPS), 3 were congenital lobar overinflation (CLO) and 1 was a benign tumour). Of the 73 antenatal cases, 33(45%) were congenital pulmonary airway malformations (CPAM), 23(32%) BPS, 9(12%) CLO, 4(5%) "others" and 4(5%) normal CT. 37(54%) were resected due to size of lesions, feeder vessels or parental choice. Ten (7 CPAM, 2 BPS and 1 CLO) required early surgery for respiratory distress or recurrent chest infections. One neonate died after surgery due to prematurity. 32(46%) were managed conservatively and monitored over median duration of 12m (range: 1-72m). None of these children had lower respiratory tract infections or malignancy.Conclusions: This study revealed that 19% of CTM in Wales required surgery. Low complication rate exists for small CTM managed conservatively in the medium term and its results could be utilised for parental counselling with regards to treatment.FootnotesCite this article as: European Respiratory Journal 2020; 56: Suppl. 64, 2826.This abstract was presented at the 2020 ERS International Congress, in session “Respiratory viruses in the "pre COVID-19" era”.This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only). ER -