RT Journal Article
SR Electronic
T1 Late Breaking Abstract - Risk factors of mortality for COVID-19 patients in a North East London cohort: a retrospective analysis
JF European Respiratory Journal
JO Eur Respir J
FD European Respiratory Society
SP 3594
DO 10.1183/13993003.congress-2020.3594
VO 56
IS suppl 64
A1 Daryl Cheng
A1 Kiran Desai
A1 Claire Calderwood
A1 Anastasia Otamas
A1 Natasha O'Sullivan
A1 Adam Ainley
YR 2020
UL http://erj.ersjournals.com/content/56/suppl_64/3594.abstract
AB Background: There is a growing body of literature on COVID-19 suggesting decreased survival with increasing age, in black and minority ethnic patients (BAME), and with comorbidities such as diabetes mellitus and obesity.Aims: To evaluate whether these risk factors were relevant in a cohort of COVID-19 patients admitted to a large North East London NHS trust serving 3 boroughs with a highly diverse population.Method: Data was collected for 215 patients from 10/03/2020–26/04/2020 for retrospective analysis. 209 patients with confirmed or clinically suspected COVID-19 admitted to 3 respiratory wards were included in the final analysis.Results: Most patients were male (66.0%). 77 patients died during the data collection period (32%). 32.4% of patients had pre-existing diabetes, and 14.4% had pre-existing obesity. 118 patients were of White ethnicity (56.5%), 43 Asian (20.6%), 28 Black (13.4%), 4 Mixed (1.9%) and 16 Other (7.7%). In a Cox proportional hazards model, there was a significant difference in survival for patients >65 years old (HR 6.12, 2.20-17.1, p < 0.001). There was a no significant difference in survival for patients based on sex, pre-existing diabetes, obesity or ethnicity.Conclusion: In contrast to international data and despite serving a population with rich ethnic diversity, COVID-19 infection in our cohort was most prevalent in white patients. The unchanged survival between white and BAME groups may reflect the high measures of deprivation in the local population. To better understand these findings continued investigation into the local demographics and variations are critical to stratify risk and to help plan for further peaks in the pandemic.FootnotesCite this article as: European Respiratory Journal 2020; 56: Suppl. 64, 3594.This abstract was presented at the 2020 ERS International Congress, in session “Respiratory viruses in the "pre COVID-19" era”.This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only).