TY - JOUR T1 - Clinical-epidemiological study of lipoid pneumonia in infants JF - European Respiratory Journal JO - Eur Respir J DO - 10.1183/13993003.congress-2020.3110 VL - 56 IS - suppl 64 SP - 3110 AU - Paula Serrano Soares AU - Ludmila Pereira Barbosa Dos Santos AU - Letícia Oliveira Dias AU - Robson De Alvarenga Facina AU - Thereza Fonseca Quirico Dos Santos AU - Selma Maria De Azevedo Sias Y1 - 2020/09/07 UR - http://erj.ersjournals.com/content/56/suppl_64/3110.abstract N2 - Introduction: Lipoid pneumonia (LP) is caused by the inhalation or aspiration of oily substances. It is commonly underdiagnosed due to similarity with other diseases of the respiratory tract such as pneumonia or tuberculosis. In Brazil, the most common cause of LP is the aspiration of mineral oil (MO).Objective: To describe the clinical-epidemiological profile of LP diagnosed at pediatric bronchoscopy service in Hospital Universitário Antônio Pedro (HUAP), Niterói, Rio de Janeiro, Brazil.Methodology: Observational, retrospective (2006-2019) study, using medical records and database from pediatric bronchoscopy service and hematology and cytology laboratories of HUAP.Results: 21 infants with LP were analyzed, 61,9% were male, mean age=5,1±4,2 months; the mean time of MO use was 20,3±31 days, used for constipation in 90,5% of cases. The main symptoms were: tachypnea (100%), cough (76,2%), fever (66,7%) and dyspnea (61,9%). Chest HRCT showed bilateral pulmonary consolidations in 95,2% of the cases, with right lung predominance (52,4%). Among the 19 patients who performed a white blood cell count, the majority had leukocytosis (18989,5±6876 cel/mm³), neutrophils (56,6±17,2%). In 95,2% of the cases, there was no early diagnosis of LP, and they were treated with more than one antimicrobial scheme. Bronchoalveolar lavage (BAL) confirmed the diagnosis of LP through Sudan or Oil red.Conclusion: Infants are more affected in the first semester of life. Symptoms, radiology and leukogram are similar to bacterial pneumonia. MO should not be used in infants due to risk of aspiration and LP. The diagnostic suspicion of LP becomes important in infants who used mineral oil.FootnotesCite this article as: European Respiratory Journal 2020; 56: Suppl. 64, 3110.This abstract was presented at the 2020 ERS International Congress, in session “Respiratory viruses in the "pre COVID-19" era”.This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only). ER -