RT Journal Article
SR Electronic
T1 Spirometry as an integral part of benign tracheal stenosis management
JF European Respiratory Journal
JO Eur Respir J
FD European Respiratory Society
SP 2844
DO 10.1183/13993003.congress-2020.2844
VO 56
IS suppl 64
A1 Josué Pinto
A1 Bruno Chambel
A1 Cláudia Freitas
A1 Mariana Conceição
A1 António Morais
A1 Gabriela Fernandes
A1 Adriana Magalhães
A1 Hélder Novais Bastos
YR 2020
UL http://erj.ersjournals.com/content/56/suppl_64/2844.abstract
AB Background: Benign tracheal stenosis (BTS) management is challenging. Though bronchoscopy is the gold standard for diagnosis, its inherent risks make it a less than ideal follow-up method. Previous studies from the 70s established spirometry as a quantitative tool for evaluation of BTS, but scarce research was conducted since. This study aimed to correlate spirometric values with anatomical grading and severity of BTS.Methods: Patients with BTS followed in our department were recruited. Data was collected by patient interview and by consulting the clinical file. Respiratory function tests and cervico-thoracic imaging were performed within 6 months. Stenosis severity was measured using image analysis software applied to radiological images. Data analysis was performed to assess the correlation between spirometric values and stenosis features.Results: Of 28 patients enrolled (mean age 55.1±15.9 years, 53.6% female), 89.3% had complex stenosis. The most common etiology was post-intubation (67.8%) and the most common location was subglottic (71.4%). Regarding stenosis severity, 60.7% presented <50% of airway narrowing. Tracheal narrowing >50% was associated with higher FEV1/PEF ratio and lower PEF% value (p=0.042 and p=0.045, respectively). FEV1/PEF ratio was the only spirometric parameter that accurately classified those with >50% tracheal narrowing (AUC=0.80). There was no significant association between spirometric values and stenosis complexity. Remarkably, the number of endoscopic procedures during follow-up was inversely correlated with quality of life (r=-0.427, p=0.023).Conclusion: Spirometry is a potential method to predict BTS severity, thus reducing the need of diagnostic bronchoscopies during follow-up.FootnotesCite this article as: European Respiratory Journal 2020; 56: Suppl. 64, 2844.This abstract was presented at the 2020 ERS International Congress, in session “Respiratory viruses in the "pre COVID-19" era”.This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only).