TY - JOUR T1 - Prescriptions for treatment in patients with PCD: does clinical routine match recommendations? JF - European Respiratory Journal JO - Eur Respir J DO - 10.1183/13993003.congress-2020.3504 VL - 56 IS - suppl 64 SP - 3504 AU - Eugénie Noémie Rachel Collaud AU - Agatha Wisse AU - Eva Sophie Lunde Pedersen AU - Barben Juerg AU - Christian Clarenbach AU - Andreas Jung AU - Philipp Latzin AU - Romain Lazor AU - Lurà Marco AU - Isabelle Rochat AU - Myrofora Goutaki AU - Claudia Kuehni Y1 - 2020/09/07 UR - http://erj.ersjournals.com/content/56/suppl_64/3504.abstract N2 - There are no evidence-based treatment guidelines for Primary Ciliary Dyskinesia (PCD). Treatments vary between and within countries. Generally accepted management recommendations include immunization for pneumococcus and influenza, physical activity, nasal therapy, physiotherapy and antibiotic treatment in patients with infections. We aim to describe recommended management by physicians in Switzerland for patients with PCD on immunizations, physical activity, nasal therapy, and physiotherapy.Methods: We included all patients in the Swiss PCD registry with available clinical records from January 2010 to November 2018. We used prescribed treatment from the most recent clinical encounters. We calculated the proportion of patients for whom immunization, nasal therapy, physiotherapy and physical activity was prescribed stratified for age (<18 and >18 years).Results: We included 55 patients (mean age 27(IQR 1-71) years, 45% female). Physicians prescribed nasal therapy in 60% (n=33), physiotherapy in 60% (n=33), immunization in 29% (=16) and recommended physical activity in 18% (n=10). Physicians prescribed nasal therapy (82%), physiotherapy (76%), and physical activity (24%) more often to children compared with adults (55%, 55%, 16%) and immunization more often to adults (37%) compared with children (12%).Conclusion: This is the first study describing management recommendations made by physicians in a Swiss population with PCD. A high proportion of patients with PCD did not received generally recommended treatments, and there were systematic differences between adult and children. It highlights the need for increased awareness amongst physicians and for more standardized care of PCD patients.FootnotesCite this article as: European Respiratory Journal 2020; 56: Suppl. 64, 3504.This abstract was presented at the 2020 ERS International Congress, in session “Respiratory viruses in the "pre COVID-19" era”.This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only). ER -