RT Journal Article
SR Electronic
T1 Study of current trend of thoracic malignancy in young adults at a tertiary care center
JF European Respiratory Journal
JO Eur Respir J
FD European Respiratory Society
SP 1690
DO 10.1183/13993003.congress-2020.1690
VO 56
IS suppl 64
A1 Darshan Kumar Bajaj
A1 Surya Kant
A1 Richa Tyagi
A1 Jyoti Bajpai
A1 Abhishek Dubey
A1 R A S Kushwaha
A1 Ajay Kumar Verma
A1 K Vignesh
A1 Mona Asnani
YR 2020
UL http://erj.ersjournals.com/content/56/suppl_64/1690.abstract
AB Objective: Incidence of cancer has risen markedly in younger age groups over the recent years&is believed to have a poorer prognosis with an aggressive course.The present research was undertaken to study the current scenario of thoracic malignancy in young adults.Methods: The study was conducted over a timeline of one year(Oct 2018-19) at K G Medical University,Lucknow,India.24 Patients between the age group of 18-35 years with suspected lung malignancy were investigated using various modalities including bronchoscopy,thoracoscopy&transthoracic biopsy followed by immunohistochemistry.The diagnosed patients were put on treatment& a 6 months follow up of the cohort was done.Results: Diagnosis could be established in 21 patients(87.5%) out of 24 while 3 expired.The predominant histological subtype was adenocarcinoma(40%) followed by mesothelioma(20%).There was no significant gender preponderance observed in the proven cases (M:F=4:3).Most of the patients were offered chemotherapy &palliative care(86%) as they reported in late stages of disease i.e. Stage IIIB&IV.However 3 patients with miscellaneous diagnosis i.e. 2 of Ewing’s sarcoma and 1 of peripheral nerve sheath tumor were referred for surgery.9 patients expired whereas rest remained stable at 6 months of follow up.Conclusion: Lung cancer in young age is a distinctive disease having socioeconomic implications.Majority of them are non-smokers.As the predominant histological subtype is adenocarcinoma,there is increased likelihood of positive driver gene mutations so efforts should be made for the individualized targeted therapy.Environmental factors&unhealthy lifestyle do play a role.More research is required to study the unidentified causes.FootnotesCite this article as: European Respiratory Journal 2020; 56: Suppl. 64, 1690.This abstract was presented at the 2020 ERS International Congress, in session “Respiratory viruses in the "pre COVID-19" era”.This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only).