RT Journal Article SR Electronic T1 Smoking status and in-hospital outcomes of ST elevation myocardial infarction patients in a Brazilian public university hospital JF European Respiratory Journal JO Eur Respir J FD European Respiratory Society SP 3062 DO 10.1183/13993003.congress-2020.3062 VO 56 IS suppl 64 A1 Alessandra Hofstadler Deiques Fleig A1 Isabella Brixner A1 Natalia Colissi A1 Alessandra Boesing A1 Andressa Seehaber A1 Luiz Fiori A1 Bruna Santos A1 Alexandra Cardoso A1 Alessandro Anversa A1 Matheus Donadel A1 Stefano Aita A1 Marcelo Silva A1 Clandio Marques A1 Jacqueline Vaz A1 Marcia Schmidt A1 Carlos Gottschall A1 Alexandre Quadros A1 Mateus Marques A1 Anibal Abelin YR 2020 UL http://erj.ersjournals.com/content/56/suppl_64/3062.abstract AB Background: Prior studies have found that smokers with ST-segment elevation myocardial infarction (STEMI) are younger, have fewer coexisting high-features and lower mortality than nonsmokers.Objectives: To evaluate the relationship between cigarette smoking status and in-hospital outcomes of patients treated with STEMI at a tertiary hospital.Methods: Prospective cohort study of a single center. Patients admitted with STEMI between September 2016 and September 2019 were included. Smoking status was categorized as never-smokers, current smokers and former smokers. Clinical characteristics, length of stay, all-cause mortality and major cardiovascular events (MACE, defined as the composite of total mortality, re-infarction, stroke and cardiac arrest) during the in-hospital period were evaluated. Chi-square test, ANOVA and Tukey test, and the Kruskal-Wallis H test were used, as appropriate. P<.05 was considered statistically significant.Results: Of the 230 patients hospitalized with STEMI in the period, 92 (40%) were currently smoking and 63 (27.3%) were former smokers. Current smokers (57.2±11.4 years) were younger than never-smokers (63.7±11.4 years) (p = 0.001) and former smokers (64.8±9.6 years) (p<0.001). Baseline characteristics and use of reperfusion therapy were unrelated to smoking status. Never-smokers, current smokers and former smokers had similar median length of stay, in-hospital mortality (6.8% vs. 9.9% vs. 11.3%, respectively, p=0.65) and MACE (p=0.41).Conclusion: Compared to never-smokers and former smokers, current smoking is associated with the occurrence of STEMI at a younger age and with similar in-hospital mortality.FootnotesCite this article as: European Respiratory Journal 2020; 56: Suppl. 64, 3062.This abstract was presented at the 2020 ERS International Congress, in session “Respiratory viruses in the "pre COVID-19" era”.This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only).