%0 Journal Article %A Danielle Strens %A Benjamin Bondue %A Caroline Dahlqvist %A Hans Slabbynk %A Julien Guiot %A Guy F. Joos %A Natacha Gusbin %A Wim Janssens %A Antoine Froidure %A Wim Wuyts %T Management-related costs of Idiopathic Pulmonary Fibrosis (IPF) in Belgium %D 2020 %R 10.1183/13993003.congress-2020.4810 %J European Respiratory Journal %P 4810 %V 56 %N suppl 64 %X Introduction: Costs related to IPF management are a major concern.Aims and Objectives: To assess real life costs for the medical management of IPF in Belgium based on PROOF-NEXT registry, a prospective longitudinal and observational study set in Belgium and Luxembourg.Methods: We included all antifibrotic naïve patients with at least 3 months follow up since enrollment, between 2014 and 2019. Direct costs were calculated by multiplying each item of resource use, obtained from each individual patient chart, with its corresponding unit cost (2020, €) using the National Institute for Health and Disability Insurance perspective (NIHDI). We used a Kaplan–Meier sample average estimator to weigh expected costs by the probability of survival and to adjust for censored data (shorter follow up). Lung transplant costs are excluded (reason for leaving the registry).Results: We included 179 patients (80.4% male patients, mean age 70.9 years). The average observation time was 18.5 months. 88% of patients received AF therapy, pirfenidone being the first line treatment in 71% of cases, 9.5% received pulmonary rehabilitation. Mean overall cost/patient for the first year was 23,707€, 24,688€ for the second year and 22,797€ for the third year. Costs were driven by AF therapy cost (88.5%) followed by rehabilitation cost (5.6%).Conclusions: Management costs of IPF are mainly driven by AF therapy but are not increasing over time.FootnotesCite this article as: European Respiratory Journal 2020; 56: Suppl. 64, 4810.This abstract was presented at the 2020 ERS International Congress, in session “Respiratory viruses in the "pre COVID-19" era”.This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only). %U