PT - JOURNAL ARTICLE AU - Tamisier, Renaud AU - Treptow, Erika AU - Joyeux-Faure, Marie AU - Lévy, Patrick AU - Sapène, Marc AU - Benmerad, Meriem AU - Bailly, Sébastien AU - Grillet, Yves AU - Stach, Bruno AU - Muir, Jean-François AU - Pegliasco, Hervé AU - Pépin, Jean-Louis TI - Impact of a multimodal telemonitoring intervention on CPAP adherence in symptomatic low-cardiovascular risk sleep apnea: a randomized controlled trial AID - 10.1183/13993003.congress-2020.4739 DP - 2020 Sep 07 TA - European Respiratory Journal PG - 4739 VI - 56 IP - suppl 64 4099 - http://erj.ersjournals.com/content/56/suppl_64/4739.short 4100 - http://erj.ersjournals.com/content/56/suppl_64/4739.full SO - Eur Respir J2020 Sep 07; 56 AB - Background: One of the major challenges in treating obstructive sleep apnea (OSA) is to achieve adequate continuous positive airway pressure (CPAP) adherence. We determined the effect of a multimodal telemonitoring intervention on CPAP adherence, quality of life and functional status in symptomatic OSA patients with low cardiovascular risk.Study Design and Methods: In a multicenter, randomized controlled trial, newly diagnosed OSA patients were randomly assigned to multimodal telemonitoring(TM) for 6 months vs usual care (UC). TMconsisted ofbuilt-in electronic alert algorithms for early adjustment of CPAP treatment in case of side effects, leaks or persistent residual events.The outcomesincluded CPAP adherence, daily symptoms such as fatigue and sleepiness, and quality of life.Results: Of 206 OSA patients aged 50.6 [42.1;58.1] (median [IQR]) years;predominantly male (63%) with body mass index of 30.6 [26.8;35.1] kg/m2and an AHI of 45.2 [34.0;60.0] events/hour) 102 received UC and 104 TM. After 6 months of treatment, CPAPadherence was similar in the two groups when assessed either by mean duration of usage (4.73±2.48 hours/night in the TM group and 5.08±2.44 hours/night in the UC group, p=0.30) or in % of patients adherent to treatment (over 4 hours usage/night, > 70% nights; 64% in TM vs 72% in UC, p=0.24). There was no significant difference between the groups in effect size of improvement in fatigue and sleepiness.Interpretation: In severe OSA patients with low cardiovascular risk, multimodal telemonitoring did not increase CPAP adherence. For both TM and UC groups similar improvements in daytime symptoms were achieved.FootnotesCite this article as: European Respiratory Journal 2020; 56: Suppl. 64, 4739.This abstract was presented at the 2020 ERS International Congress, in session “Respiratory viruses in the "pre COVID-19" era”.This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only).