TY - JOUR T1 - Sublobar resection versus lobectomy in non-small cell lung cancer: a propensity matched analysis JF - European Respiratory Journal JO - Eur Respir J DO - 10.1183/13993003.congress-2020.4090 VL - 56 IS - suppl 64 SP - 4090 AU - Antonio Francisco Honguero Martinez AU - Carlos Eduardo Almonte-García AU - María Peyró-Sánchez AU - Marta Genovés-Crespo AU - Cora Sampedro-Salinas AU - Francisco-Javier Callejas-González AU - Raúl Godoy-Mayoral AU - María-Dolores García-Jiménez AU - Claudia-Rossana Rodríguez-Ortega AU - Patricia López-Miguel AU - Ana-María-Del-Rosario Núñez-Ares AU - Nuria Gutiérrez-González AU - Wanda-Mayoris Almonte-Batista AU - Javier Cruz-Ruiz AU - Sergio García-Castillo AU - Miguel-Ángel Moscardó-Orenes AU - Jesús Jiménez-López AU - Pablo León-Atance Y1 - 2020/09/07 UR - http://erj.ersjournals.com/content/56/suppl_64/4090.abstract N2 - Objective: this study analyses long-term results of sublobar resection in daily clinical activity versus the standard procedure (lobectomy).Method: From a prospective database, patients treated with sublobar resection for NSCLC were identified (2007-2017). None of them had malignant disease in the 5 previous years nor induction treatment. Log-rank test was used to compare overall survival and disease free survival. One-to-one propensity score matching was performed for age, sex, stage, and comorbities to reduce bias selection.Results: 1214 patients were surgically treated for lung cancer in that period of time. Finally, 52 patients were included in sublobar group with following resections: pulmonary wedge 37(71.2%) cases; anatomic segmentectomy 15(28.8%) cases. Women 4(7.7%); Men 48(92.3%). Mean age: 68.6 y.o. (range 42-86). Pulmonary function test (FEV1 64.9% vs 77.3% p=0.004) and tumoral size (1.9cm vs 3.0cm p<0.001) were lower in the sublobar resection group. PET-TC uptake was higher in lobectomy group (SUVmax 7.6 vs 5.6 p=0.050). stage I-A 27 cases (51.9%)stage I-B 15 cases (28.8%)stage II-A 1 case (1.9%)stage II-B 7 cases (13.5%)stage III-A 2 cases (3.8%)Overall survival showed no statistically differences: 90.7 months for sublobar resection group; 91.2 months for lobectomy group (p=0.951). Disease free survival was longer for lobectomy group (93.5 months) than for sublobar group (66.3 months), although with no statistical significant difference (p=0.087).Conclusion: In selected cases, sublobar resection can reach an overall survival similar to lobectomy. Multicenters studies are needed to confirm these results.FootnotesCite this article as: European Respiratory Journal 2020; 56: Suppl. 64, 4090.This abstract was presented at the 2020 ERS International Congress, in session “Respiratory viruses in the "pre COVID-19" era”.This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only). ER -